Sharifi Sheila, Spires Andrew, Dender Lauren, Nouri Keyvan
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, USA.
John Sealy School of Medicine, The University of Texas Medical Branch, Galveston, USA.
Lasers Med Sci. 2025 Apr 8;40(1):182. doi: 10.1007/s10103-025-04438-3.
Laser hair removal (LHR) plays a significant role in gender-affirming care of transgender and gender-diverse patients. This systematic review aims to synthesize and critically evaluate the current literature on the utility of LHR in these populations, while addressing limitations and barriers.
A search of the PubMed, EMBASE and Web of Science databases was conducted according to PRISMA guidelines. Studies were included if they directly discussed the topic, were of the appropriate study type and were published in peer-reviewed journals in English. Our search yielded 10 studies that met our inclusion criteria. From the included studies, data was individually extracted and scrutinized, following formal quality assessment.
In transwomen receiving vaginoplasty, LHR has been established as an effective method for preprocedural hair removal, with preliminary studies comparing its efficacy to electrolysis. In transmen undergoing phalloplasty, early findings suggest LHR as satisfactory in decreasing hair density in the neourethra. While limited, available evidence indicates that adequate hair removal may contribute to improved psychosocial outcomes. Efficacy of LHR prior to gender-affirming surgery may differ based on treatment protocols and patient demographics, potentially contributing to the variability in results included within our review. Moreover, cost, lack of provider expertise, and overall fear and anxiety remain recognized barriers to care for LHR and electrolysis.
These results highlight the significant role of LHR in the gender-affirming care of transgender individuals, by aiding in surgical readiness and facilitating gender congruence. Our review is subject to several limitations including limited sample sizes, underscoring the need for future research.
激光脱毛(LHR)在跨性别和性别多样化患者的性别确认护理中发挥着重要作用。本系统评价旨在综合并批判性评估当前关于LHR在这些人群中的效用的文献,同时解决局限性和障碍。
根据PRISMA指南对PubMed、EMBASE和科学网数据库进行检索。如果研究直接讨论该主题、属于适当的研究类型且以英文发表在同行评审期刊上,则纳入研究。我们的检索产生了10项符合纳入标准的研究。从纳入的研究中,在进行正式的质量评估后,分别提取并审查数据。
在接受阴道成形术的跨性别女性中,LHR已被确立为术前脱毛的有效方法,初步研究将其疗效与电解法进行了比较。在接受阴茎成形术的跨性别男性中,早期研究结果表明LHR在降低新尿道的毛发密度方面令人满意。虽然证据有限,但现有证据表明充分的脱毛可能有助于改善心理社会结果。LHR在性别确认手术前的疗效可能因治疗方案和患者人口统计学特征而异,这可能导致我们综述中结果的变异性。此外,成本、缺乏提供者专业知识以及总体恐惧和焦虑仍然是LHR和电解法护理公认的障碍。
这些结果突出了LHR在跨性别者性别确认护理中的重要作用,有助于手术准备并促进性别认同。我们的综述存在一些局限性,包括样本量有限,这凸显了未来研究的必要性。