Jarrar Tareq, Jafar Hamam Younes, Al Kayed Hadeel Abdallah, Alrabadi Bassel Esmat, Milhem Ayham Kamel, Alqatawna Maryam Hisham, Odaibat Husam
Al-Quds University, Jerusalem, Palestine.
University of Jordan, Amman, Jordan.
Urol Case Rep. 2025 Mar 15;60:103011. doi: 10.1016/j.eucr.2025.103011. eCollection 2025 May.
Renal cell carcinoma (RCC) is a rare but significant cause of secondary hypertension. Chromophobe RCC represents 5 % of all RCC cases, with renin secretion being even rarer. We report a case of a 32-year-old female with six-month history of uncontrolled hypertension. Laboratory findings showed elevated plasma renin and aldosterone levels. Imaging revealed a large left renal mass. After radical nephrectomy, histopathology confirmed chromophobe RCC. Her blood pressure normalized postoperatively, and she was normotensive at 1-month follow-up. This case underscores the importance of considering renal tumors in hypertensive patients and the role of surgery in achieving favorable outcomes.
肾细胞癌（RCC）是继发性高血压的一种罕见但重要的病因。嫌色性肾细胞癌占所有肾细胞癌病例的5%，肾素分泌更为罕见。我们报告一例32岁女性，有6个月未控制的高血压病史。实验室检查结果显示血浆肾素和醛固酮水平升高。影像学检查发现左肾有一个大肿块。根治性肾切除术后，组织病理学证实为嫌色性肾细胞癌。她的血压术后恢复正常，1个月随访时血压正常。该病例强调了在高血压患者中考虑肾肿瘤的重要性以及手术在取得良好预后中的作用。
