Jackson P
J Laryngol Otol. 1985 Jul;99(7):667-70. doi: 10.1017/s0022215100097450.
In the preceeding report (Jackson, 1985) the author produced evidence which brought into question the widely held view that, in abolishing tinnitus, lidocaine was acting 'centrally'. This present investigation is another approach to attempt to narrow the site of action of lidocaine in abolishing tinnitus. During a four-year period, patients suffering from strictly unilateral tinnitus which was referred to, and therefore apparently arising from, an ipsilateral 'dead' ear, underwent electrocochleography. Additionally, the subjective effect on the tinnitus of a bolus injection of lidocaine was recorded. Nine patients were available for this study, which appears to show a correlation of the results of the electrocochleogram and the effects of the lidocaine injection, although the numbers are small.
在前一份报告（杰克逊，1985年）中，作者提出了证据，对广泛持有的一种观点提出了质疑，即利多卡因在消除耳鸣时起“中枢”作用。本次研究是试图缩小利多卡因消除耳鸣作用部位的另一种方法。在四年时间里，对患有严格单侧耳鸣的患者进行了电耳蜗图检查，这些患者被转诊，因此耳鸣显然起源于同侧“死”耳。此外，记录了一次大剂量注射利多卡因对耳鸣的主观影响。有九名患者参与了这项研究，尽管人数较少，但似乎显示出电耳蜗图结果与利多卡因注射效果之间的相关性。
