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[耳鸣的治疗。鼓室内注入利多卡因和类固醇溶液]

[Therapy of tinnitus. Tympanic cavity infusion of lidocaine and steroid solution].

作者信息

Sakata E, Nakazawa H, Iwashita N

出版信息

Auris Nasus Larynx. 1984;11(1):11-8. doi: 10.1016/s0385-8146(84)80012-7.

DOI:10.1016/s0385-8146(84)80012-7
PMID:6732647
Abstract

Tinnitus is an otological symptom which is often encountered and is yet difficult to treat. If tinnitus is of cochlear origin then it seems reasonable to assume that a total depression of the cochlear function will abolish cochlear tinnitus. To achieve this depression, transtympanic injections of a local anesthetic (4% Lidocaine) to anesthetize the inner ear and of Decadoron were conducted in a patient suffering from tinnitus. One hundred and sixty-eight patients (220 ears) who had suffered from relatively long-term tinnitus were included in this study. In almost all of the cases the clinical symptoms and the otological findings (i.e., the audiogram and caloric test) indicated that the probable lesion underlying the tinnitus was located within the end organ. In some cases this injection brought a transient (for few days), slight, neurosensorial deafness in the low-frequency range. This auditory disorder, however, was completely restored without sequelae. Our results are summarized as follows: in 76 ears, tinnitus was abolished completely, in 109 ears, tinnitus was considerably ameliorated, in 35 ears, tinnitus was slightly ameliorated or no effect. One hundred and nine patients (138 ears) who had suffered from tinnitus were included in this study. Decadoron was applied to the middle ear cavity by transtympanic injection. Our results are summarized as follows: in 87 ears, tinnitus was abolished, in 39 ears, tinnitus was considerably ameliorated, in 14 ears, tinnitus was slightly ameliorated or no effect.

摘要

耳鸣是一种常见但难以治疗的耳科症状。如果耳鸣起源于耳蜗,那么可以合理推测,耳蜗功能的完全抑制将消除耳蜗性耳鸣。为实现这种抑制,对一名耳鸣患者进行了经鼓膜注射局部麻醉剂(4%利多卡因)以使内耳麻醉以及注射地塞米松的操作。本研究纳入了168例(220耳)患有相对长期耳鸣的患者。几乎在所有病例中,临床症状和耳科检查结果(即听力图和冷热试验)表明,耳鸣潜在的病变可能位于终器内。在某些情况下,这种注射会带来短暂的(持续数天)、轻微的低频感音神经性耳聋。然而,这种听觉障碍完全恢复且无后遗症。我们的结果总结如下:76耳耳鸣完全消失,109耳耳鸣明显改善,35耳耳鸣稍有改善或无效果。本研究纳入了109例(138耳)患有耳鸣的患者。通过经鼓膜注射将地塞米松应用于中耳腔。我们的结果总结如下:87耳耳鸣消失,39耳耳鸣明显改善,14耳耳鸣稍有改善或无效果。

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[Therapy of tinnitus. Tympanic cavity infusion of lidocaine and steroid solution].[耳鸣的治疗。鼓室内注入利多卡因和类固醇溶液]
Auris Nasus Larynx. 1984;11(1):11-8. doi: 10.1016/s0385-8146(84)80012-7.
2
Treatment of cochlear tinnitus with transtympanic infusion of 4% lidocaine into the tympanic cavity.经鼓膜向鼓室注入4%利多卡因治疗耳蜗性耳鸣。
Int Tinnitus J. 2001;7(1):46-50.
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Effect of lidocaine injection of EOAE in patients with tinnitus.利多卡因注射对耳鸣患者耳声发射的影响。
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Electrocochleographic findings and the effects of lidocaine on tinnitus in non-hearing ears.电耳蜗图检查结果及利多卡因对非听力耳耳鸣的影响。
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Evaluation of Adding Lidocaine to Dexamethasone in the Intra-tympanic Injection for Management of Tinnitus: A Prospective, Randomized, Controlled Double-blinded Trial.鼓室内注射地塞米松时添加利多卡因治疗耳鸣的疗效评估:一项前瞻性、随机、对照双盲试验
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[Treatment of Ménière's disease. Middle ear infusion with lidocaine and steroid solution].[梅尼埃病的治疗。中耳注入利多卡因和类固醇溶液]
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Short Term Results of Intra Tympanic Gentamicin and Dexamethasone on Hearing and Tinnitus in Meniere's disease: A Case Control Study.鼓室内注射庆大霉素和地塞米松治疗梅尼埃病听力及耳鸣的短期疗效:一项病例对照研究
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[Treatment of tinnitus with intravenous lidocaine].[静脉注射利多卡因治疗耳鸣]
Nihon Jibiinkoka Gakkai Kaiho. 1992 Sep;95(9):1389-97. doi: 10.3950/jibiinkoka.95.1389.

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