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《环境空气污染对变应性鼻炎的影响及缓解策略建议中国专家共识》

Chinese Expert Consensus on the Impact of Ambient Air Pollution on Allergic Rhinitis and Recommendations for Mitigation Strategies.

作者信息

Xu Xu, Zhang Yuan, Cheng Lei, Fan Yunping, Han Yaozhong, Jie Ying, Li Huabin, Li Xiaobo, Liu Huanhai, Liu Jianfeng, Liu Weiwei, Lv Wei, Ma Yongjian, Ouyang Yuhui, Shan Chunguang, Shi Guanggang, Song Xicheng, Sun Shengzhi, Wang Jiajia, Wang Xiangdong, Wang Xueyan, Wang Zhenlin, Xu Yu, Yang Qintai, Zhang Yana, Zhang Yu, Zhu Dongdong, Wang Chengshuo, Chen Rui, Zhang Luo

机构信息

Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

出版信息

Allergy Asthma Immunol Res. 2025 Mar;17(2):149-164. doi: 10.4168/aair.2025.17.2.149.

DOI:10.4168/aair.2025.17.2.149
PMID:40204502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11982644/
Abstract

Ambient air pollution poses a significant yet manageable threat to human health. The growing consensus on the impact of ambient air pollutants on allergic rhinitis (AR) emphasizes the importance of prevention, control, and treatment strategies. A multidisciplinary consensus development group was established to further standardize management strategies for AR in the presence of exposure to ambient air pollutants. The quality of the evidence and the strength of the recommendations were evaluated using the grading of recommendations, assessment, development, and evaluation (GRADE) system based on domestic and international relevant medical evidence. This consensus evaluates the effects of key air pollutants on public health in relation to AR, including the synergistic effects of air pollutants with meteorological conditions and aeroallergens. At the same time, the consensus provides recommendations for targeted therapeutic and preventive measures for AR under conditions of ambient air pollution, aiming to improve AR-related health outcomes. These recommendations aim to increase public and clinical awareness of the contribution of environmental factors to AR, and offer evidence-based insights for policymakers and regulators to establish informed ambient air quality standards.

摘要

环境空气污染对人类健康构成了重大但可控的威胁。关于环境空气污染物对过敏性鼻炎(AR)影响的共识日益增加,这凸显了预防、控制和治疗策略的重要性。为了在存在环境空气污染物暴露的情况下进一步规范AR的管理策略,成立了一个多学科共识发展小组。基于国内外相关医学证据,使用推荐分级、评估、制定与评价(GRADE)系统对证据质量和推荐强度进行了评估。本共识评估了关键空气污染物对与AR相关的公众健康的影响,包括空气污染物与气象条件和空气变应原的协同效应。同时,该共识为环境空气污染条件下AR的针对性治疗和预防措施提供了建议,旨在改善与AR相关的健康结局。这些建议旨在提高公众和临床对环境因素对AR影响的认识,并为政策制定者和监管机构建立明智的环境空气质量标准提供循证见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/7b41a5fef19a/aair-17-149-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/4518ca39776e/aair-17-149-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/d897d8917166/aair-17-149-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/1e8ee73a5a0c/aair-17-149-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/7b41a5fef19a/aair-17-149-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/4518ca39776e/aair-17-149-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/d897d8917166/aair-17-149-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/1e8ee73a5a0c/aair-17-149-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f6/11982644/7b41a5fef19a/aair-17-149-g004.jpg

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Allergy. 2024 Nov;79(11):3047-3061. doi: 10.1111/all.16174. Epub 2024 May 26.
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Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021.
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Lancet. 2024 May 18;403(10440):2204-2256. doi: 10.1016/S0140-6736(24)00685-8.
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.全球疾病负担研究 2021 年在 204 个国家和地区、811 个次国家级地点对 88 种风险因素的全球负担和证据强度:系统分析。
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