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病例报告:精索巨大脂肪肉瘤。

Case Report: a giant liposarcoma of the spermatic cord.

作者信息

Wang Mingshan, Fu Yong, Liu Xiaowen, Liu Zheng

机构信息

Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Department of Urology, The Second Affiliated Hospital of Bengbu Medical University, Bengbu, China.

出版信息

Front Oncol. 2025 Mar 26;15:1490559. doi: 10.3389/fonc.2025.1490559. eCollection 2025.

DOI:10.3389/fonc.2025.1490559
PMID:40206589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11979157/
Abstract

BACKGROUND

Liposarcoma of the spermatic cord is an extremely rare urological malignancy, with fewer than 300 cases reported in the literature worldwide, and it is often difficult to distinguish from inguinal hernias and epididymal cysts. Typically, it presents as an asymptomatic, slow-growing paratesticular mass.

CASE PRESENTATION

The case described herein involves a 59-year-old man who presented to our hospital with a painless mass in the left scrotum. Physical examination revealed a fixed, firm mass in the left scrotum. Ultrasonography of the scrotum demonstrated an inhomogeneous echogenic mass measuring approximately 113 x 83 x 62 mm on the left side. Testicular MRI showed a mass in the left scrotum measuring approximately 67 x 56 x 98 mm, exhibiting isointence T1 mixed with high T2 signals. The patient then underwent surgery and pathology confirmed a liposarcoma of the spermatic cord. Currently no signs of tumor recurrence on follow-up.

CONCLUSIONS

Liposarcoma of the spermatic cord is an exceedingly rare condition, for which surgical intervention is the preferred treatment option. While there is no definitive evidence supporting the use of adjuvant radiotherapy following surgery, it remains necessary in cases where surgical margins are uncertain.

摘要

背景

精索脂肪肉瘤是一种极为罕见的泌尿系统恶性肿瘤,全球文献报道的病例不足300例,且常难以与腹股沟疝和附睾囊肿相鉴别。通常,它表现为无症状、生长缓慢的睾丸旁肿块。

病例介绍

本文所述病例为一名59岁男性,因左侧阴囊无痛性肿块前来我院就诊。体格检查发现左侧阴囊有一个固定、质地坚硬的肿块。阴囊超声显示左侧有一个不均匀回声肿块,大小约为113×83×62毫米。睾丸磁共振成像显示左侧阴囊有一个大小约为67×56×98毫米的肿块,T1加权像呈等信号,T2加权像呈高信号。该患者随后接受了手术,病理证实为精索脂肪肉瘤。目前随访未发现肿瘤复发迹象。

结论

精索脂肪肉瘤极为罕见,手术干预是首选的治疗方法。虽然没有确凿证据支持术后使用辅助放疗,但在手术切缘不确定的情况下仍有必要进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/035ed2a20a3a/fonc-15-1490559-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/51f045b9b623/fonc-15-1490559-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/9906a98d6758/fonc-15-1490559-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/91a8ddce79e2/fonc-15-1490559-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/035ed2a20a3a/fonc-15-1490559-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/51f045b9b623/fonc-15-1490559-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/9906a98d6758/fonc-15-1490559-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/91a8ddce79e2/fonc-15-1490559-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e146/11979157/035ed2a20a3a/fonc-15-1490559-g004.jpg

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本文引用的文献

1
Liposarcoma of the Spermatic Cord Mimicking an Inguinal Hernia: A Case Report and Literature Review.精索脂肪肉瘤酷似腹股沟疝:一例报告及文献复习
Cureus. 2022 Aug 22;14(8):e28269. doi: 10.7759/cureus.28269. eCollection 2022 Aug.
2
Epidemiology of Renal Cell Carcinoma: 2022 Update.肾细胞癌的流行病学:2022 年更新。
Eur Urol. 2022 Nov;82(5):529-542. doi: 10.1016/j.eururo.2022.08.019. Epub 2022 Sep 10.
3
Recursive Partitioning to Determine Order of Significance of Regional Metastasis Characteristics in Head and Neck Cutaneous Squamous Cell Carcinoma.
递归分区法确定头颈部皮肤鳞状细胞癌区域转移特征的显著性顺序。
Ann Surg Oncol. 2022 Oct;29(11):6991-6999. doi: 10.1245/s10434-022-11863-z. Epub 2022 May 15.
4
LIPOSARCOMA OF THE SPERMATIC CORD - DIAGNOSTIC AND THERAPEUTIC ISSUE.精索脂肪肉瘤——诊断与治疗问题。
Acta Clin Croat. 2021 Mar;60(1):50-54. doi: 10.20471/acc.2021.60.01.07.
5
A rare case of liposarcoma of the spermatic cord.一例罕见的精索脂肪肉瘤。
Urol Case Rep. 2020 Jul 6;33:101336. doi: 10.1016/j.eucr.2020.101336. eCollection 2020 Nov.
6
Liposarcoma of the spermatic cord presenting as an inguinal hernia.表现为腹股沟疝的精索脂肪肉瘤。
Int J Surg Case Rep. 2020;76:274-277. doi: 10.1016/j.ijscr.2020.09.195. Epub 2020 Oct 2.
7
The 2020 WHO Classification of Tumors of Soft Tissue: Selected Changes and New Entities.《2020 年世卫组织软组织肿瘤分类:精选变更和新实体》。
Adv Anat Pathol. 2021 Jan;28(1):44-58. doi: 10.1097/PAP.0000000000000284.
8
Dedifferentiated liposarcoma of the spermatic cord: Case report and review of literature.精索去分化脂肪肉瘤:病例报告及文献复习
Int J Surg Case Rep. 2020;72:418-422. doi: 10.1016/j.ijscr.2020.06.051. Epub 2020 Jun 12.
9
Dedifferentiated Liposarcoma in the Spermatic Cord Finally Diagnosed at 7th Resection of Recurrence: A Case Report and Bibliographic Consideration.精索去分化脂肪肉瘤最终在第7次复发性切除时确诊:1例病例报告及文献综述
Case Rep Oncol. 2017 Aug 9;10(2):713-719. doi: 10.1159/000479364. eCollection 2017 May-Aug.
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Asian Pac J Cancer Prev. 2015;16(8):3419-23. doi: 10.7314/apjcp.2015.16.8.3419.