Rusinova G G, Turdakova V A, Mushkacheva G S
Med Radiol (Mosk). 1985 Jul;30(7):58-62.
Thymus depopulation, DNA destruction as estimated according to the level of single-stranded breaks (SSB) and DNA structural derangement revealed by the viscosimetric assay of alkaline lysed thymocytes were observed in the course of a prolonged (1 mos) radiation exposure to tritium oxide (the 1st group) and equidimensional external gamma-irradiation (the 2nd group) in a summary dose of 10 Gy in rats. Depletion and destruction were 1.5-2 times more pronounced in case of HTO exposure. A study of the repair has revealed an increase in the number of hardly repairable or irrepairable breaks by the end of the study: by the 25th day the number of SSB repaired after additional test irradiation was O and 30% in the rats of the 1st and 2nd groups respectively.
在大鼠接受为期1个月的氧化氚（第一组）和等剂量外照射γ射线（第二组）总剂量为10 Gy的长期辐射过程中，观察到胸腺细胞耗竭、根据单链断裂（SSB）水平估算的DNA破坏以及通过碱性裂解胸腺细胞的粘度测定法揭示的DNA结构紊乱。与γ射线照射相比，氧化氚照射导致的胸腺细胞耗竭和DNA破坏程度要高1.5至2倍。修复研究表明，在实验结束时，难以修复或无法修复的断裂数量增加：在第25天，额外测试照射后修复的单链断裂数量在第一组和第二组大鼠中分别为0和30%。
