Shorokhova V B, Mushkacheva G S
Radiobiologiia. 1988 May-Jun;28(3):393-6.
Disturbance and normalization of nucleic acid metabolism in rat thymus was studied after the effect of tritium oxide delivered in similar cumulative doses but at different dose rates. Both the disturbance and normalization were shown to be a function of dose rate, the slightest damage and the complete recovery being registered at the lowest dose rate (the amount of tritium oxide administered being 0.37 MBq/g/day). The rate of restoration was also a function of dose rate; with tritium oxide dose of 1.85 MBq/g/day (the dose rate at the stage of the equilibrium tritium content in the aqueous phase being 0.38 Gy/day) it was 9 times as high as that after a dose of 0.37 MBq/g/day (0.11 Gy/day dose rate).
研究了以相似累积剂量但不同剂量率给予氧化氚后大鼠胸腺核酸代谢的紊乱与恢复情况。结果表明，紊乱和恢复均为剂量率的函数，在最低剂量率（氧化氚给药量为0.37MBq/g/天）时损伤最小且能完全恢复。恢复速率也是剂量率的函数；当氧化氚剂量为1.85MBq/g/天（水相中氚平衡含量阶段的剂量率为0.38Gy/天）时，恢复速率是剂量为0.37MBq/g/天（剂量率为0.11Gy/天）后的9倍。
