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关于喂养方式及其母亲妊娠期糖尿病与婴儿人体测量学变化关系的评估:一项初步研究。

Evaluation of Changes in the Anthropometric Measurements of Infants in Relation to the Type of Feeding and the Presence of Gestational Diabetes in Their Mothers: A Preliminary Study.

作者信息

Ćwiek Dorota, Zimny Małgorzata, Dawid Weronika, Iwanowicz-Palus Grażyna, Kulesza-Brończyk Bożena, Rachubińska Kamila, Cybulska Anna Maria, Sipak-Szmigiel Olimpia, Branecka-Woźniak Dorota, Szymoniak Katarzyna

机构信息

Department of Obstetrics and Pathology of Pregnancy, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 71-210 Szczecin, Poland.

Obstetrics Development, Faculty of Health Sciences, Medical University of Lublin, 20-081 Lublin, Poland.

出版信息

J Clin Med. 2025 Mar 31;14(7):2393. doi: 10.3390/jcm14072393.

Abstract

: Breastfeeding is widely regarded as the optimal method of infant nutrition. A notable benefit of breastfeeding is its potential to avert the development of childhood overweight and obesity. This assertion holds particular significance in the context of infants whose mothers have exhibited gestational diabetes, a condition that has been demonstrated to be associated with an increased risk of carbohydrate and/or fat disorders in offspring, potentially leading to the onset of overweight and obesity in later life. : The objective of the present study was to examine the variations in the anthropometric dimensions of infants across three distinct time points during the initial year of life, with a particular focus on the correlation between infant feeding practices and the prevalence of gestational diabetes in maternal subjects. Additionally, this study encompassed an analysis of the disparities in anthropometric dimensions between infant males and females. : The study population included 42 infants whose mothers had been diagnosed with gestational diabetes between the 24th and 28th week of pregnancy, as well as 28 infants of women without gestational diabetes. The infants' dietary habits, including breastfeeding, mixed feeding, and formula feeding, were assessed, and their anthropometric measurements were obtained at three time points: 7 ± 1 weeks postpartum, 6 months ± 1 week postpartum, and 12 months ± 1 week postpartum. The infants were measured for weight, length, head circumference, and thickness of the subscapular skin fold. We also calculated their BMI and Ponderal Index, and the measurements were referenced to WHO centile grids. : At 7 ± 1 weeks postpartum, exclusively breastfed infants exhibited higher weight compared to those who were mixed-fed or formula-fed ( = 0.03). However, at 1 year of age, breastfed infants demonstrated significantly lower weight compared to formula-fed infants ( = 0.019). Furthermore, at 12 months, breastfed boys exhibited lower weight, length, BMI, and lower subscapular skinfold thickness compared to formula-fed infants. : Breastfeeding has been shown to play a pivotal role in preventing obesity in children. In the initial postnatal period, infants who are fed breast milk exhibit a higher weight compared to those who are fed formula. However, by the age of 12 months, the weight of breastfed infants typically falls below that of formula-fed infants. Diabetes during pregnancy has been observed to have no impact on the anthropometric dimensions of infants up to the age of one. Nevertheless, further research is necessary to comprehensively assess the long-term implications of maternal GDM in their offspring.

摘要

母乳喂养被广泛认为是婴儿营养的最佳方式。母乳喂养的一个显著益处是其有可能避免儿童期超重和肥胖的发生。这一论断在母亲患有妊娠期糖尿病的婴儿背景下具有特别重要的意义,妊娠期糖尿病已被证明与后代碳水化合物和/或脂肪代谢紊乱风险增加有关,可能导致日后超重和肥胖的发生。

本研究的目的是在婴儿出生后的第一年的三个不同时间点检查婴儿人体测量维度的变化,特别关注婴儿喂养方式与母亲受试者妊娠期糖尿病患病率之间的相关性。此外,本研究还分析了男婴和女婴在人体测量维度上的差异。

研究人群包括42名母亲在怀孕第24至28周被诊断患有妊娠期糖尿病的婴儿,以及28名母亲无妊娠期糖尿病的妇女所生的婴儿。评估了婴儿的饮食习惯,包括母乳喂养、混合喂养和配方奶喂养,并在三个时间点获取了他们的人体测量数据:产后7±1周、产后6个月±1周和产后12个月±1周。测量了婴儿的体重、身长、头围和肩胛下皮褶厚度。我们还计算了他们的BMI和体质指数,并将测量结果参照世界卫生组织百分位数标准。

产后7±1周时,纯母乳喂养的婴儿体重高于混合喂养或配方奶喂养的婴儿(P = 0.03)。然而,在1岁时,母乳喂养的婴儿体重明显低于配方奶喂养的婴儿(P = 0.019)。此外,在12个月时,与配方奶喂养的婴儿相比,母乳喂养的男婴体重、身长、BMI和肩胛下皮褶厚度更低。

母乳喂养已被证明在预防儿童肥胖方面起着关键作用。在出生后的最初阶段,母乳喂养的婴儿体重高于配方奶喂养的婴儿。然而,到12个月大时,母乳喂养婴儿的体重通常低于配方奶喂养的婴儿。已观察到孕期糖尿病对1岁以内婴儿的人体测量维度没有影响。然而,有必要进行进一步研究以全面评估母亲妊娠期糖尿病对其后代的长期影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3747/11989845/240a5d1c94e6/jcm-14-02393-g001.jpg

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