Wan Yu-Xuan, Li Guo-Qing, Duan Sai-Li, Chang Shi
Department of General Surgery, Xiangya Hospital Central South University, Changsha, Hunan, P.R. China.
Clinical Research Center for Thyroid Disease in Hunan Province, Changsha, Hunan, P.R. China.
Semin Ophthalmol. 2025 Apr 14:1-13. doi: 10.1080/08820538.2025.2490669.
Thyroid eye disease, the most frequent extra-thyroid manifestation of Graves' disease, has puzzled physicians and scientists and could potentially make patients sight-threatened. This study aimed to aid researchers and readers in this field to improve their understanding of thyroid eye disease research trends and provide ideas for future research from unique perspectives.
The top 100 most-cited papers on Graves' ophthalmopathy from January 1, 2010, to December 31, 2022, were retrieved from the Web of Science Core Collection database. Two authors defined and analyzed these data independently via CiteSpace, Vosviewer, and Tableau.
A total of 1861 publications linked with Graves' ophthalmopathy research were identified. All of these 100 top-cited papers were published between 2010 and 2022, and the United States of America (USA), Italy, Germany, England, Netherlands, and China made significant contributions to Graves' ophthalmopathy research. The journal with the highest number of published papers is the Journal of Clinical Endocrinology & Metabolism ( = 22). The USA was the most productive country in this topic ( = 29). The Johannes Gutenberg University of Mainz had the largest number of publications ( = 8) and citations ( = 1610). The most cited article was 'MECHANISMS OF DISEASE Graves' Ophthalmopathy'. The clustered network and timeline of keywords showed the prevalence, diagnosis, and treatment of thyroid eye disease, which were the research core themes during the past 12 years.
This study provided insights into the most influential studies related to thyroid eye disease via analyzing the top 100 most-cited papers in thyroid eye disease research.
甲状腺眼病是格雷夫斯病最常见的甲状腺外表现，一直困扰着医生和科学家，并且可能对患者的视力构成威胁。本研究旨在帮助该领域的研究人员和读者更好地理解甲状腺眼病的研究趋势，并从独特视角为未来研究提供思路。
从科学网核心合集数据库中检索2010年1月1日至2022年12月31日期间关于格雷夫斯眼病被引用次数最多的100篇论文。两位作者通过CiteSpace、Vosviewer和Tableau独立定义和分析这些数据。
共识别出1861篇与格雷夫斯眼病研究相关的出版物。这100篇被引用次数最多的论文均发表于2010年至2022年之间，美国、意大利、德国、英国、荷兰和中国对格雷夫斯眼病研究做出了重大贡献。发表论文数量最多的期刊是《临床内分泌与代谢杂志》（=22篇）。美国是该主题研究成果最多的国家（=29篇）。美因茨约翰内斯·古腾堡大学的出版物数量最多（=8篇），被引用次数最多（=1610次）。被引用次数最多的文章是《疾病机制：格雷夫斯眼病》。关键词聚类网络和时间线展示了甲状腺眼病的患病率、诊断和治疗情况，这些是过去12年的研究核心主题。
本研究通过分析甲状腺眼病研究中被引用次数最多的100篇论文，深入了解了与甲状腺眼病相关的最具影响力的研究。
