Mathersul Danielle C, Schulz-Heik R Jay, Avery Timothy J, Allende Santiago, Zeitzer Jamie M, Bayley Peter J
School of Psychology, Murdoch University, Murdoch, WA 6150, Australia.
Centre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University, Murdoch, WA 6150, Australia.
Depress Anxiety. 2023 Aug 14;2023:7001667. doi: 10.1155/2023/7001667. eCollection 2023.
Sleep disturbances are a prominent feature of posttraumatic stress disorder (PTSD), and poorer sleep quality is associated with higher PTSD severity. This highlights the importance of monitoring sleep outcomes alongside PTSD symptoms in treatments targeting PTSD. Yet few studies monitor both sleep and PTSD outcomes, unless sleep is the primary treatment target. Furthermore, inconsistencies remain about the effects of first-line, evidence-based PTSD treatments on sleep.
Here, we explored changes in sleep in secondary analyses from a randomised controlled trial that originally assessed the noninferiority of a breathing-based yoga practice (Sudarshan kriya yoga; SKY) to a first-line PTSD treatment (cognitive processing therapy (CPT)) for clinically significant PTSD symptoms among US veterans (intent-to-treat = 85; per protocol = 59). Sleep was assessed via subjective (self-reported sleep diary), PTSD symptom severity items (self-reported and clinician-administered insomnia/nightmare sleep items), and objective (wrist actigraphy) measures.
Following treatment, subjective sleep diary measures of quality, latency, and wake duration showed small effect size ( = .24 - .39) improvements, with no significant differences between treatment groups. Significant improvements were also observed in PTSD sleep symptoms, though CPT ( = .34) more reliably reduced nightmares while SKY ( = .44-.45) more reliably reduced insomnia. In contrast, there were no significant treatment-related effects for any of the actigraphy-measured sleep indices.
To our knowledge, this is the first study to investigate sleep as an outcome of CPT or SKY for PTSD, across a combination of subjective diary, PTSD symptom severity, and objective actigraphic measures. Findings lend support to a growing body of evidence that trauma-focused psychotherapy for PTSD improves sleep and suggest that yoga-based interventions may also be beneficial for sleep among individuals with emotional or mental health disorders like PTSD. This trial is registered with NCT02366403.
睡眠障碍是创伤后应激障碍(PTSD)的一个突出特征,睡眠质量较差与PTSD严重程度较高相关。这凸显了在针对PTSD的治疗中,除了监测PTSD症状外,同时监测睡眠结果的重要性。然而,很少有研究同时监测睡眠和PTSD结果,除非睡眠是主要治疗目标。此外,关于一线循证PTSD治疗对睡眠的影响仍存在不一致之处。
在此,我们在一项随机对照试验的二次分析中探讨了睡眠变化,该试验最初评估了一种基于呼吸的瑜伽练习(苏达山克里亚瑜伽;SKY)与一线PTSD治疗(认知加工疗法(CPT))在美国退伍军人中对具有临床意义的PTSD症状的非劣效性(意向性治疗 = 85;符合方案 = 59)。通过主观(自我报告的睡眠日记)、PTSD症状严重程度项目(自我报告和临床医生管理的失眠/噩梦睡眠项目)和客观(手腕活动记录仪)测量来评估睡眠。
治疗后,主观睡眠日记中关于质量、潜伏期和清醒持续时间的测量显示出小效应量( = 0.24 - 0.39)的改善,治疗组之间无显著差异。在PTSD睡眠症状方面也观察到显著改善,尽管CPT( = 0.34)更可靠地减少了噩梦,而SKY( = 0.44 - 0.45)更可靠地减少了失眠。相比之下,对于任何通过活动记录仪测量的睡眠指标,均未观察到与治疗相关的显著影响。
据我们所知,这是第一项通过主观日记、PTSD症状严重程度和客观活动记录仪测量相结合的方式,将睡眠作为CPT或SKY治疗PTSD的结果进行研究的试验。研究结果支持了越来越多的证据,即针对PTSD的创伤聚焦心理治疗可改善睡眠,并表明基于瑜伽的干预措施可能对患有PTSD等情绪或精神健康障碍的个体的睡眠也有益。该试验已在ClinicalTrials.gov注册,注册号为NCT02366403。