Fu Xiaolong, Wang Si, Wu Yunhao, Sun Yu, Liu Wenwen, Xi Xin, Li Geng-Lin, Liu Ke, Yuan Wei, Chen Fangyi, Wang Hongyang, Yang Tao, Liu Yuhe, Zheng Jialin, Shi Haibo, Qu Jing, Chen Xiaowei, Suo Limin, Huang Yideng, Xu Xinbo, Tang Xuxia, Li Xiaojun, Xu Lei, Gao Xia, Yu Lisheng, Shu Yilai, Zhang Weiqi, Sun Jinpeng, Yuan Huijun, Gong Shusheng, Li Wenyan, Ma Xiulan, Zha Dingjun, Gao Jiangang, Li Huawei, He Zuhong, Liu Guang-Hui, Pei Gang, Kong Weijia, Wang Haibo, Chai Renjie
Shandong Provincial Hospital, Medical Science and Technology Innovation Center, School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China.
Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China.
Life Med. 2025 Mar 7;4(1):lnaf011. doi: 10.1093/lifemedi/lnaf011. eCollection 2025 Feb.
Hearing is one of the most vital sensory functions in human beings and a crucial means of perceiving and acquiring information from the natural environment. The advancement of human society is closely linked to the development of language, with hearing serving as the foundation for verbal communication. As individuals age, the deterioration of the auditory system becomes a significant factor contributing to sensory impairments in the elderly. In addition to hearing loss, the aging of the auditory system is also associated with cognitive decline and psychosocial disorders, which severely impact the quality of life for older adults. Currently, there are no effective treatments or interventions available for addressing the aging of the auditory system. Therefore, identifying biomarkers of the auditory system aging is of great significance. The Aging Biomarker Consortium of China has conducted a comprehensive evaluation of aging biomarkers in the auditory system, focusing on three dimensions: morphological, functional, and humoral biomarkers. This initiative aims to establish a foundation for assessing the degree of aging in the auditory system and to promote the management of auditory health in an aging society, ultimately enhancing the auditory health of the elderly population both in China and globally.
听力是人类最重要的感官功能之一，也是从自然环境中感知和获取信息的关键手段。人类社会的进步与语言的发展紧密相连，听力是言语交流的基础。随着个体年龄的增长，听觉系统的衰退成为导致老年人感觉障碍的一个重要因素。除了听力损失外，听觉系统的老化还与认知能力下降和心理社会障碍有关，这严重影响了老年人的生活质量。目前，尚无有效的治疗方法或干预措施来应对听觉系统的老化。因此，识别听觉系统老化的生物标志物具有重要意义。中国衰老生物标志物联盟对听觉系统的衰老生物标志物进行了全面评估，重点关注三个维度：形态学、功能和体液生物标志物。该倡议旨在为评估听觉系统的老化程度奠定基础，并促进老龄化社会中听觉健康的管理，最终提高中国乃至全球老年人群的听觉健康水平。
