脑衰老生物标志物框架：衰老生物标志物联盟的共识声明
A framework of biomarkers for brain aging: a consensus statement by the Aging Biomarker Consortium.
作者信息
Jia Yu-Juan, Wang Jun, Ren Jun-Rong, Chan Piu, Chen Shengdi, Chen Xiao-Chun, Chhetri Jagadish K, Guo Junhong, Guo Qihao, Jin Lingjing, Liu Qiang, Liu Qiang, Ma Wenlin, Mao Zhiyong, Song Moshi, Song Weihong, Tang Yi, Wang Difei, Wang Peijun, Xiong Lize, Ye Keqiang, Zhang Junjian, Zhang Weiqi, Zhang Xiaoqing, Zhang Yunwu, Zhang Zhanjun, Zhang Zhuohua, Zheng Jialin, Liu Guang-Hui, Eve Sun Yi, Wang Yan-Jiang, Pei Gang
机构信息
Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing 400042, China.
Department of Neurology, First Affiliated Hospital, Shanxi Medical University, Taiyuan 030001, China.
出版信息
Life Med. 2023 May 6;2(3):lnad017. doi: 10.1093/lifemedi/lnad017. eCollection 2023 Jun.
China and the world are facing severe population aging and an increasing burden of age-related diseases. Aging of the brain causes major age-related brain diseases, such as neurodegenerative diseases and stroke. Identifying biomarkers for the effective assessment of brain aging and establishing a brain aging assessment system could facilitate the development of brain aging intervention strategies and the effective prevention and treatment of aging-related brain diseases. Thus, experts from the Aging Biomarker Consortium (ABC) have combined the latest research results and practical experience to recommend brain aging biomarkers and form an expert consensus, aiming to provide a basis for assessing the degree of brain aging and conducting brain-aging-related research with the ultimate goal of improving the brain health of elderly individuals in both China and the world.
中国和世界正面临着严峻的人口老龄化以及与年龄相关疾病负担日益加重的问题。大脑衰老会引发主要的与年龄相关的脑部疾病，如神经退行性疾病和中风。识别用于有效评估大脑衰老的生物标志物并建立大脑衰老评估系统，有助于制定大脑衰老干预策略以及有效预防和治疗与衰老相关的脑部疾病。因此，衰老生物标志物联盟（ABC）的专家们结合了最新研究成果和实践经验，推荐大脑衰老生物标志物并形成专家共识，旨在为评估大脑衰老程度和开展与大脑衰老相关的研究提供依据，最终目标是改善中国乃至全球老年人的大脑健康状况。
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