亚急性硬化性全脑炎和急性麻疹中的低分子量麻疹免疫球蛋白M
Low molecular weight measles immunoglobulin M in subacute sclerosing panencephalitis and acute measles.
作者信息
Connolly J H, Simpson D M, Trudgett A, Hopkins A P
出版信息
Postgrad Med J. 1985 May;61(715):407-10. doi: 10.1136/pgmj.61.715.407.
Thirty eight patients with subacute sclerosing panencephalitis (SSPE) were investigated. Five patients who previously had measles immunoglobulin M (IgM) detected in unfractionated serum and cerebrospinal fluid (CSF) had measles IgM exclusively in the low molecular weight (LMW) fractions of serum and CSF. Measles IgM had previously not been found in unfractionated serum from 33 patients but was detected exclusively in the LMW fractions of serum from 30 patients. Seven children with acute measles had the expected high molecular weight (HMW) measles IgM in serum but 5 also had LMW measles IgM. Four young adults who had had measles in childhood had neither HMW nor LMW measles IgM in their sera.
对38例亚急性硬化性全脑炎（SSPE）患者进行了研究。5例先前在未分级血清和脑脊液（CSF）中检测到麻疹免疫球蛋白M（IgM）的患者，其麻疹IgM仅存在于血清和脑脊液的低分子量（LMW）组分中。33例患者的未分级血清中先前未发现麻疹IgM，但在30例患者的血清LMW组分中仅检测到麻疹IgM。7例急性麻疹患儿血清中具有预期的高分子量（HMW）麻疹IgM，但5例也有LMW麻疹IgM。4例儿童期患过麻疹的年轻成年人血清中既没有HMW也没有LMW麻疹IgM。
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