亚急性硬化性全脑炎：从淋巴结活检中分离出被抑制的麻疹病毒。
Subacute sclerosing panencephalitis: isolation of suppressed measles virus from lymph node biopsies.
作者信息
Horta-Barbosa L, Hamilton R, Wittig B, Fuccillo D A, Sever J L, Vernon M L
出版信息
Science. 1971 Aug 27;173(3999):840-1. doi: 10.1126/science.173.3999.840.
PMID:4937231
Abstract
Measles virus was isolated in mixed cultures of lymph node cells and HeLa cells. The agent was isolated by cocultivation from biopsy specimens of two of five patients with subacute sclerosing panencephalitis. The virus was identified by hemagglutination-inhibition, immunofluorescent, and neutralization tests. Biopsies from controls did not show evidence of measles virus.
摘要
在淋巴结细胞和HeLa细胞的混合培养物中分离出麻疹病毒。通过共培养从5例亚急性硬化性全脑炎患者中的2例的活检标本中分离出该病原体。通过血凝抑制、免疫荧光和中和试验鉴定该病毒。对照组的活检未显示麻疹病毒的迹象。
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