韦尼克脑病中的可逆性昏迷。
Reversible coma in Wernicke's encephalopathy.
作者信息
Gibb W R, Gorsuch A N, Lees A J, Yudkin J S
出版信息
Postgrad Med J. 1985 Jul;61(717):607-10. doi: 10.1136/pgmj.61.717.607.
Abstract
A case of coma due to Wernicke's encephalopathy complicated by respiratory failure is described. Ventilation and thiamine administration lead to recovery, although Korsakoff's psychosis and ataxia persisted. A review of similar cases of coma emphasizes the absence of diagnostic features, but that if structural disease is excluded the presence of pupillary and ocular signs may support a diagnosis of Wernicke's encephalopathy. The response to thiamine may be diagnostic as in 8 of these patients who received it, but the long-term morbidity remains high.
摘要
本文描述了一例因韦尼克脑病并发呼吸衰竭而导致昏迷的病例。尽管科萨科夫精神病和共济失调持续存在，但通气和硫胺素治疗使患者康复。对类似昏迷病例的回顾强调了缺乏诊断特征，但如果排除结构性疾病，瞳孔和眼部体征的存在可能支持韦尼克脑病的诊断。对硫胺素的反应可能具有诊断意义，就像这些接受硫胺素治疗的患者中有8例那样，但长期发病率仍然很高。
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