Juskeviciute Akvile, Resch Milda Aleknonyte, Kumle Bernhard, Busch Hans Jörg, Janssens Uwe, Michels Guido, Herda Lars Roman, Faber Martin, Merz Sabine, Reindl Michael, Wasser Christoph, Kornstaedt Stefan, Langguth Patrick, Schulte Kevin, Bernhard Michael, Pin Martin, Schunk Domagoj
Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Department of Business Informatics (Process Analytics), Christian-Albrechts-University of Kiel, Kiel, Germany.
BMC Emerg Med. 2025 Apr 15;25(1):63. doi: 10.1186/s12873-025-01216-w.
The procedures and locations where patients are admitted to hospitals and subsequently diagnosed after out-of-hospital cardiac arrest (OHCA) in Germany exhibit considerable heterogeneity. Specifically, advanced imaging diagnostic methods via computed tomography (CT) show significant variation in both timing and execution. However, echocardiography (ECHO) is not an alternative to CT in this setting, as both modalities serve distinct diagnostic purposes. This study aimed to comprehensively analyze the status quo analysis of current procedures in German emergency departments (EDs) regarding early-phase (within the first six hours) CT imaging diagnostics after resuscitation and the treatment of critically ill patients in the ED resuscitation room.
An anonymized cross-sectional study was conducted from November 28, 2023, to February 18, 2024, using an online survey platform ( https://www.surveymonkey.de ) with a standardized questionnaire. The survey targeted 994 medical directors of German EDs and was distributed through the mailing lists of the German Society for Interdisciplinary Emergency and Acute Medicine (DGINA) and the German Interdisciplinary Association for Intensive Care and Emergency Medicine (DIVI). The Medical Faculty of Christian-Albrechts-University Kiel granted ethical approval (D 586/22). An expert panel reviewed the questionnaire to ensure validity and minimize bias. All statistical analyses, including both descriptive and inferential statistics, were conducted using R software.
Out of 994 hospitals contacted, 182 hospitals from 15 German federal states participated, yielding a response rate of 18.3%. The overall completion rate for the whole questionnaire was 12.2% (n = 121/994). In the survey, 9.6% (n = 15/157) of hospitals reported having CT within the resuscitation room, while 70.1% (n = 119/157) had CT within a range of 50 m of the resuscitation room. A standard operating procedure (SOP)/postresuscitation protocol for patients suffering from OHCA was available for 61.1% (n = 88 yes, n = 56 no) of the hospitals. A specific postresuscitation CT protocol (postrCT protocol) was used by 30.0% (n = 48 yes, n = 93 no) of the hospitals, with 59.2% (n = 29) receiving a head-to-pelvis CT (whole-body CT). In hospitals without a CT protocol (n = 84), echocardiography (82.1%, n = 69), abdominal ultrasound (61.9%, n = 52), and non-contrast CT of the head (47.6%, n = 40) are used for distinctive diagnostics. Cardiac Arrest Center (CAC)-certified hospitals were significantly more likely to have a SOP/postresuscitation protocol (91.9 vs. 49.0%, p < 0.001) and a specific postrCT protocol (63.2 vs. 22.1%, p < 0.001) than noncertified hospitals.
Currently, there is no nationwide standardized protocol for imaging diagnosis in patients after OHCA in German EDs. Protocols are more often used in CAC hospitals in Germany then in non-certified hospitals. Given the limitations of survey-based research, results should be interpreted with caution regarding their representativeness across all German EDs and further prospective studies including mortality and neurological outcomes are warranted.
在德国,院外心脏骤停(OHCA)患者入院及后续诊断的流程和地点存在显著异质性。具体而言,通过计算机断层扫描(CT)进行的高级影像诊断方法在时间安排和实施方面存在显著差异。然而,在这种情况下,超声心动图(ECHO)并非CT的替代方法,因为这两种检查方式具有不同的诊断目的。本研究旨在全面分析德国急诊科(EDs)当前关于复苏后早期(六小时内)CT影像诊断以及急诊科复苏室危重症患者治疗的现状。
2023年11月28日至2024年2月18日,使用在线调查平台(https://www.surveymonkey.de )及标准化问卷进行了一项匿名横断面研究。该调查针对德国994名急诊科医疗主任,通过德国跨学科急诊与急性医学协会(DGINA)和德国重症监护与急诊医学跨学科协会(DIVI)的邮件列表进行分发。基尔大学医学院给予了伦理批准(D 586/22)。一个专家小组对问卷进行了审核,以确保有效性并尽量减少偏差。所有统计分析,包括描述性统计和推断性统计,均使用R软件进行。
在联系的994家医院中,来自德国15个联邦州的182家医院参与了调查,回复率为18.3%。整个问卷的总体完成率为12.2%(n = 121/994)。在调查中,9.6%(n = 15/157)的医院报告在复苏室内配备了CT,而70.1%(n = 119/157)的医院在复苏室50米范围内设有CT。61.1%(n = 88家回答是,n = 56家回答否)的医院有针对OHCA患者的标准操作程序(SOP)/复苏后方案。30.0%(n = 48家回答是,n = 93家回答否)的医院使用了特定的复苏后CT方案(postrCT方案),其中59.2%(n = 29家)进行了头部至骨盆的CT检查(全身CT)。在没有CT方案的医院(n = 84家)中,超声心动图(82.1%,n = 69家)、腹部超声(61.9%,n = 52家)和头部非增强CT(47.6%,n = 40家)用于鉴别诊断。获得心脏骤停中心(CAC)认证的医院比未认证的医院更有可能拥有SOP/复苏后方案(91.9%对49.0%,p < 0.001)和特定的postrCT方案(63.2%对22.1%,p < 0.001)。
目前,德国急诊科对于OHCA患者的影像诊断尚无全国性标准化方案。方案在德国的CAC认证医院中比在未认证医院中使用得更频繁。鉴于基于调查研究的局限性,对于其在所有德国急诊科中的代表性,结果应谨慎解读,并且有必要开展包括死亡率和神经学转归的进一步前瞻性研究。