Suppr超能文献

饮用水中抗生素抗性基因的检测:秘鲁亚马逊地区一所大学的研究

Detection of Antibiotic-Resistance Genes in Drinking Water: A Study at a University in the Peruvian Amazon.

作者信息

Chayña Euclides Ticona, Ferro Pompeyo, Morales-Rojas Eli, Ferro-Gonzales Ana Lucia, Nuñez Jorge Bautista, Pedraza Edwaldo Villanueva, Florindes Jorge Antonio Malca, Ferro-Gonzales Polan

机构信息

Facultad de Ciencias Naturales y Aplicadas, Universidad Nacional Intercultural Fabiola Salazar Leguía de Bagua, Jr. Ancash Nro. 520, Bagua 01721, Peru.

Instituto de Investigación en Tecnologías de Información y Comunicación (IITIC), Facultad de Ingeniería y Sistemas y Mecánica Eléctrica, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, Jr. Libertad Nro 1300, Bagua 01721, Peru.

出版信息

Int J Environ Res Public Health. 2025 Feb 27;22(3):353. doi: 10.3390/ijerph22030353.

Abstract

This study investigated the presence of antibiotic-resistance genes in drinking water consumed by the university community in the Peruvian Amazon. Water samples were collected from three primary sources: inflow from the distribution network, a storage cistern, and an underground intake. Conventional PCR was employed to detect genes associated with resistance to erythromycin (), ampicillin (), ciprofloxacin (), multidrug resistance (), and specific multidrug resistance in (). Physicochemical analysis revealed compliance with most regulatory standards; however, groundwater samples showed lead concentrations exceeding legal limits (0.72 mg/L) and lacked residual chlorine. All sampling points tested positive for the evaluated resistance genes, demonstrating the widespread dissemination of resistance factors in drinking water. Contrary to initial expectations, resistance genes were also prevalent in treated sources. These findings reveal a critical public health risk for the university community, emphasising the need for effective disinfection systems and robust monitoring protocols to ensure water safety. The presence of these resistance genes in water is a critical public health concern as it can facilitate the spread of resistant bacteria, reducing the effectiveness of medical treatments and increasing the risk of infections that are difficult to control.

摘要

本研究调查了秘鲁亚马逊地区大学社区所饮用的饮用水中抗生素抗性基因的存在情况。水样采集自三个主要来源:配水管网的进水、一个储水池以及一个地下取水口。采用常规聚合酶链反应(PCR)来检测与对红霉素()、氨苄青霉素()、环丙沙星()、多重耐药性()以及()中特定多重耐药性相关的基因。物理化学分析表明大多数指标符合监管标准;然而,地下水样本显示铅浓度超过法定限值(0.72毫克/升)且缺乏余氯。所有采样点的评估抗性基因检测均呈阳性,表明抗性因子在饮用水中广泛传播。与最初预期相反,抗性基因在经过处理的水源中也很普遍。这些发现揭示了大学社区面临的重大公共卫生风险,强调需要有效的消毒系统和严格的监测方案以确保水安全。水中这些抗性基因的存在是一个重大的公共卫生问题,因为它会促进耐药细菌的传播,降低医疗治疗的效果,并增加难以控制的感染风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fe8/11942251/dac7b30ee2c9/ijerph-22-00353-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验