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《全面综述:化学成分、药理机制及在食品和保健品中的工业应用》

Comprehensive Review of : Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products.

作者信息

Yi Dandan, Wang Zhiyong, Peng Mu

机构信息

College of Biological and Food Engineering, Hubei Minzu University, Enshi 445000, China.

出版信息

Foods. 2025 Apr 3;14(7):1252. doi: 10.3390/foods14071252.

DOI:10.3390/foods14071252
PMID:40238536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11988686/
Abstract

(L.) Britt., a multifunctional herbaceous plant, is widely used in traditional medicine and cuisine due to its rich array of bioactive compounds. To date, many key phytochemicals in have been identified, including volatile terpenoids (perillaldehyde, limonene,), flavonoids (luteolin, apigenin), and phenolic acids (rosmarinic acid derivatives), which exhibit significant antioxidant, anti-inflammatory, antiviral, anticancer, antibacterial, and blood sugar-lowering effects. Studies have shown that volatile oils, flavonoids, and phenolic acids in exert their effects in various experimental models. In food and industrial applications, shows innovative potential in functional foods, natural preservatives, and novel food additives, effectively extending food shelf life and providing antimicrobial protection. Moreover, research on the biology and genetic improvement of has provided new approaches to enhance its yield and bioactive content. Finally, this paper also discusses the safety and standardization issues of the plant, providing theoretical support for its widespread application.

摘要

(唇形科)薄荷,一种多功能草本植物,因其丰富的生物活性化合物而被广泛应用于传统医学和烹饪中。迄今为止,已鉴定出薄荷中的许多关键植物化学物质,包括挥发性萜类化合物(紫苏醛、柠檬烯)、黄酮类化合物(木犀草素、芹菜素)和酚酸(迷迭香酸衍生物),它们具有显著的抗氧化、抗炎、抗病毒、抗癌、抗菌和降血糖作用。研究表明,薄荷中的挥发油、黄酮类化合物和酚酸在各种实验模型中发挥作用。在食品和工业应用中,薄荷在功能性食品、天然防腐剂和新型食品添加剂方面显示出创新潜力,有效延长食品保质期并提供抗菌保护。此外,对薄荷生物学和遗传改良的研究为提高其产量和生物活性成分提供了新方法。最后,本文还讨论了该植物的安全性和标准化问题,为其广泛应用提供理论支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cb/11988686/c15fc1d58a65/foods-14-01252-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cb/11988686/3b9af8de0543/foods-14-01252-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cb/11988686/25afeaabdcb3/foods-14-01252-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cb/11988686/c15fc1d58a65/foods-14-01252-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cb/11988686/3b9af8de0543/foods-14-01252-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cb/11988686/25afeaabdcb3/foods-14-01252-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cb/11988686/c15fc1d58a65/foods-14-01252-g003.jpg

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本文引用的文献

1
Luteolin inhibits inflammation and M1 macrophage polarization in the treatment of Pseudomonas aeruginosa-induced acute pneumonia through suppressing EGFR/PI3K/AKT/NF-κB and EGFR/ERK/AP-1 signaling pathways.木犀草素通过抑制表皮生长因子受体/磷脂酰肌醇-3激酶/蛋白激酶B/核因子κB和表皮生长因子受体/细胞外信号调节激酶/激活蛋白-1信号通路,在治疗铜绿假单胞菌诱导的急性肺炎中抑制炎症和M1巨噬细胞极化。
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Genetic variations in FAD3 and its influence on agronomic traits and fatty acid composition in perilla germplasm.紫苏种质中FAD3基因的遗传变异及其对农艺性状和脂肪酸组成的影响。
Plant Sci. 2025 Jun;355:112452. doi: 10.1016/j.plantsci.2025.112452. Epub 2025 Mar 1.
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A Novel Natural Penetration Enhancer for Transdermal Drug Delivery: In Vitro/In Vivo Evaluation and Penetration Enhancement Mechanism.
一种用于透皮给药的新型天然渗透促进剂:体外/体内评价及渗透增强机制
Pharmaceutics. 2025 Feb 14;17(2):254. doi: 10.3390/pharmaceutics17020254.
4
Perillaldehyde targeting PARP1 to inhibit TRPM2-CaMKII/CaN signal transduction in diabetic cardiomyopathy.紫苏醛靶向聚(ADP-核糖)聚合酶1以抑制糖尿病性心肌病中的瞬时受体电位阳离子通道蛋白2-钙/钙调神经磷酸酶依赖性蛋白激酶II/钙调神经磷酸酶信号转导
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Antibiofilm efficacies and mechanism of perillaldehyde against Shewanella putrefaciens.紫苏醛对腐败希瓦氏菌的抗生物膜效果及作用机制
Food Microbiol. 2025 Jun;128:104699. doi: 10.1016/j.fm.2024.104699. Epub 2024 Nov 30.
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Adv Sci (Weinh). 2025 Apr;12(14):e2412152. doi: 10.1002/advs.202412152. Epub 2025 Feb 14.
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Foods. 2024 Dec 27;14(1):47. doi: 10.3390/foods14010047.
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