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蜥蜴麻醉——一家兽医医院23年(2000 - 2023年)麻醉方案及麻醉过程监测质量的回顾性研究

Lizard anesthesia-a retrospective study of anesthetic protocol and monitoring quality of anesthetic episodes at a veterinary hospital over 23 years (2000-2023).

作者信息

Gise Braxton T, Thorbrogger Chloe J, Rasys Ashley M, Quandt Jane E, Divers Stephen J

机构信息

1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA.

2Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD.

出版信息

J Am Vet Med Assoc. 2025 Apr 16;263(7):904-913. doi: 10.2460/javma.24.11.0728. Print 2025 Jul 1.

Abstract

OBJECTIVE

This study's aim was to summarize the anesthetic events of lizards seen at a university hospital, identify challenges with record-keeping, and assess anesthesia-related mortality.

METHODS

From October 2000 through January 2023, medical records of lizards that underwent general anesthesia were reviewed. Cases with complete anesthesia records were used to assess anesthetic parameters. Collected data included general patient details, diagnosis, procedures, premedication, induction, maintenance, monitoring, and recovery. The recorded duration of each of these periods, when documented, was reported for each patient, alongside what drug protocols were utilized and compiled to give an overarching view of trends in anesthesia at the hospital. The times were also analyzed to assess whether any drug/protocol led to more negative outcomes or prolonged anesthetic duration.

RESULTS

A total of 104 anesthetic events were performed. Ninety-nine cases had detailed reports available for analysis. A records review identified issues that frequently resulted in poor record management and highlighted the most used anesthetic agents. For premedications, alfaxalone, butorphanol, midazolam, and hydromorphone were common. During induction, alfaxalone or propofol was the most common. For maintenance, isoflurane and sevoflurane were comparable, while alfaxalone was favored for noninhalants. Of the 99 cases analyzed, 95 recovered, 3 were euthanatized due to poor prognosis, and 1 failed to recover; the 1 that failed to recover had significant underlying disease identified.

CONCLUSIONS

The trend of maintenance alfaxalone constant rate infusions replacing inhalants is the major development. The records for anesthesia have improved over time, with the exception of anesthesia time records. It is recommended to implement an automated system that records vitals intermittently alongside implementation of an updated anesthesia sheet with areas dedicated to common research values.

CLINICAL RELEVANCE

General anesthesia can be reliably and safely undertaken in lizards without severe pre-existing disease. Efforts should focus on identifying preexisting disease, creating uniform systems for assessing anesthetic stages, and limiting record-keeping variance.

摘要

目的

本研究旨在总结某大学医院蜥蜴的麻醉情况,确定记录保存方面的挑战,并评估麻醉相关死亡率。

方法

回顾2000年10月至2023年1月期间接受全身麻醉的蜥蜴的病历。具有完整麻醉记录的病例用于评估麻醉参数。收集的数据包括患者一般详细信息、诊断、手术、术前用药、诱导、维持、监测和恢复情况。若有记录,报告每位患者上述各阶段的记录时长,以及所使用的药物方案,并汇总以全面了解医院的麻醉趋势。还对这些时间进行分析,以评估是否有任何药物/方案导致更多负面结果或延长麻醉时长。

结果

共进行了104例麻醉。99例有详细报告可供分析。病历审查发现了经常导致记录管理不善的问题,并突出了最常用的麻醉剂。术前用药方面,阿法沙龙、布托啡诺、咪达唑仑和氢吗啡酮较为常见。诱导期间,阿法沙龙或丙泊酚最为常用。维持阶段,异氟烷和七氟烷使用情况相当,而非吸入麻醉剂则更倾向于使用阿法沙龙。在分析的99例病例中,95例恢复,3例因预后不良实施安乐死,1例未恢复;未恢复的1例存在明显的基础疾病。

结论

维持阶段阿法沙龙持续输注取代吸入麻醉剂是主要发展趋势。随着时间推移,麻醉记录有所改善,但麻醉时间记录除外。建议实施自动间歇性记录生命体征的系统,并采用更新后的麻醉记录单,设置专门记录常见研究数据的区域。

临床意义

对于无严重基础疾病的蜥蜴,可可靠且安全地实施全身麻醉。应致力于识别基础疾病,建立统一的麻醉阶段评估系统,并减少记录差异。

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