Fu Chunpeng, Fu Xiaopeng, Li Zongzhen, Xu Chengjiang, Li Fajun, Wang LiXin, Wang Lifang
Shandong Peninsula Engineering Research Center of Comprehensive Brine Utilization, Weifang University of Science and Technology, Shouguang, China.
Marine and Fishery Supervision Detachment of Rizhao City, Rizhao, China.
Microbiol Spectr. 2025 Jun 3;13(6):e0314824. doi: 10.1128/spectrum.03148-24. Epub 2025 Apr 17.
The intestinal microbiota of is critical for its health and disease resistance, but imbalances can increase the risk of infections, especially by pathogenic species. This study used the 2bRAD-M method to analyze the effects of dietary chitosan oligosaccharide (COS) supplementation on the gut microbiota of . Shrimp were fed diets with COS at 5‰ and 10‰ levels. Results showed that as COS concentration increased, beneficial microbial taxa (e.g., Bacteroidetes, Actinobacteria, and ) significantly increased, while harmful bacteria decreased. For example, abundance dropped from 0.084 in controls to 0.033 in the 5‰ group, and decreased from 0.216 in controls to 0.121 and 0.021 in the 5‰ and 10‰ groups, respectively. also declined from 0.244 in controls to 0.049 and 0.094 in the 5‰ and 10‰ groups. These findings indicate that COS supplementation can enhance beneficial microbes and reduce harmful bacteria in intestines. This study highlights COS as a sustainable dietary intervention to improve shrimp health and reduce antibiotic use in aquaculture.
This study demonstrates that dietary chitosan oligosaccharide (COS) supplementation can effectively modulate the intestinal microbiota of . At 5‰ and 10‰ levels, COS increased beneficial bacteria (e.g., Bacteroidetes and Actinobacteria) while reducing harmful pathogens like and . This shift enhances nutrient absorption, immune function, and disease resistance in shrimp. COS thus offers a sustainable alternative to antibiotics in aquaculture, promoting healthy growth and reducing environmental impact.
[具体对象]的肠道微生物群对其健康和抗病能力至关重要，但微生物群失衡会增加感染风险，尤其是由致病性[具体物种]引起的感染。本研究采用2bRAD - M方法分析了添加壳寡糖（COS）对[具体对象]肠道微生物群的影响。给虾投喂添加了5‰和10‰水平COS的饲料。结果表明，随着COS浓度的增加，有益微生物类群（如拟杆菌门、放线菌门和[具体类群]）显著增加，而有害细菌减少。例如，[具体有害菌1]丰度从对照组的0.084降至5‰组的0.033，[具体有害菌2]分别从对照组的0.216降至5‰组的0.121和10‰组的0.021。[具体有害菌3]也从对照组的0.244降至5‰组的0.049和10‰组的0.094。这些发现表明，添加COS可增强[具体对象]肠道中的有益微生物并减少有害细菌。本研究强调了COS作为一种可持续的饮食干预措施，可改善虾的健康状况并减少水产养殖中抗生素的使用。
本研究表明，添加壳寡糖（COS）可有效调节[具体对象]的肠道微生物群。在5‰和10‰水平下，COS增加了有益细菌（如拟杆菌门和放线菌门），同时减少了如[具体有害菌1]和[具体有害菌2]等有害病原体。这种变化增强了虾的营养吸收、免疫功能和抗病能力。因此，COS为水产养殖中的抗生素提供了一种可持续的替代品，促进健康生长并减少对环境的影响。
