Mirza Basil F, Krishingner Gene Austin, Campbell Kevin J
University of Florida College of Medicine, Florida, USA.
Department of Urology, University of Florida College of Medicine, Florida, USA.
Urol Res Pract. 2025 Apr 4;50(6):351-354. doi: 10.5152/tud.2025.24121.
Hypogonadism is estimated to affect up to 30% of men aged 40-70, with a range of symptoms and health implications. Despite its prevalence, its impact on resident physicians, a group known to experience high levels of stress, irregular sleep patterns, and long working hours, remains largely unexplored. This study aimed to evaluate the prevalence and impact of hypogonadism among male resident physicians.
A prospective study was conducted involving male physicians training at a tertiary referral institution. Participation was offered through distribution to Accreditation Council for Graduate Medical Education (ACGME) program coordinators and program directors. Participants were given the Androgen Deficiency in the Aging Male (ADAM) and 36-Item Short Form Health Survey questionnaires, and underwent labs including testosterone, follicle-stimulating hormone (FSH), luteinizing hormone, and estradiol levels.
Of the 651 male trainees, 27 residents were interested in participating for a response rate of 4.1%. Sixty-seven percent (18/27) completed the surveys and 22% (6/27) completed lab work. Two-thirds of the participants who completed the lab work had total testosterone levels below 400 ng/dL, and half of the participants scored positively on the ADAM questionnaire. A total of 44.4% of participants reported that their health was worse compared to a year prior.
Male resident physicians are an at-risk population for symptoms and signs of hypogonadism. This population may benefit from screening and interventions aimed at reducing the impact of hypogonadism. The findings of this study underscore the need for further research to confirm these results and explore potential interventions.
据估计，性腺功能减退影响多达30%的40至70岁男性，伴有一系列症状及对健康的影响。尽管其患病率较高，但其对住院医师（这一已知承受高压力、睡眠模式不规律且工作时间长的群体）的影响在很大程度上仍未得到探索。本研究旨在评估男性住院医师中性腺功能减退的患病率及其影响。
对在一家三级转诊机构接受培训的男性医师进行了一项前瞻性研究。通过向研究生医学教育认证委员会（ACGME）项目协调员和项目主任分发邀请参与研究。参与者被给予《老年男性雄激素缺乏症（ADAM）问卷》和《36项简短健康调查问卷》，并接受包括睾酮、促卵泡生成素（FSH）、促黄体生成素和雌二醇水平在内的实验室检查。
在651名男性受训者中，27名住院医师有兴趣参与，回复率为4.1%。67%（18/27）的人完成了调查，22%（6/27）的人完成了实验室检查。完成实验室检查的参与者中有三分之二的总睾酮水平低于400 ng/dL，且一半的参与者在ADAM问卷上得分呈阳性。共有44.4%的参与者报告称，与一年前相比，他们的健康状况变差了。
男性住院医师是出现性腺功能减退症状和体征的高危人群。这一人群可能会从旨在减少性腺功能减退影响的筛查和干预措施中受益。本研究结果强调需要进一步研究以证实这些结果并探索潜在的干预措施。
