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环境化学物质导致的先天性畸形及其他生殖危害。

Congenital malformations and other reproductive hazards from environmental chemicals.

作者信息

Sullivan F M, Barlow S M

出版信息

Proc R Soc Lond B Biol Sci. 1979 Jul 18;205(1158):91-110. doi: 10.1098/rspb.1979.0051.

DOI:10.1098/rspb.1979.0051
PMID:40245
Abstract

From a number of disasters which have already occurred throughout the world, it is known that the reproductive process in both animals and man may be severely affected by chemicals. The range of effects that might occur include not only foetal death or malformation, but also effects on the subsequent development, behaviour, intelligence and reproductive capacity of offspring which appear otherwise normal at birth. The special sensitivity of the foetus to some environmental carcinogens is also discussed. Some of the problems in screening for such effects in animals are mentioned along with the need for adequate monitoring programmes to detect reproductive toxicity both from industrial exposure to chemicals and from more general environmental exposure.

摘要

从世界各地已经发生的一些灾难可知,动物和人类的生殖过程都可能受到化学物质的严重影响。可能出现的影响范围不仅包括胎儿死亡或畸形,还包括对出生时看似正常的后代随后的发育、行为、智力和生殖能力的影响。文中还讨论了胎儿对某些环境致癌物的特殊敏感性。同时提到了在动物中筛查此类影响的一些问题,以及建立适当监测计划以检测工业化学品暴露和更广泛环境暴露所导致的生殖毒性的必要性。

相似文献

1
Congenital malformations and other reproductive hazards from environmental chemicals.环境化学物质导致的先天性畸形及其他生殖危害。
Proc R Soc Lond B Biol Sci. 1979 Jul 18;205(1158):91-110. doi: 10.1098/rspb.1979.0051.
2
Environmental causes of human congenital malformations: the pediatrician's role in dealing with these complex clinical problems caused by a multiplicity of environmental and genetic factors.人类先天性畸形的环境成因:儿科医生在应对由多种环境和遗传因素引发的这些复杂临床问题中的作用。
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Is carbon monoxide a workplace teratogen? A review and evaluation of the literature.一氧化碳是一种工作场所致畸物吗?文献综述与评估。
Ann Occup Hyg. 1990 Aug;34(4):335-47. doi: 10.1093/annhyg/34.4.335.
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引用本文的文献

1
Community study of spontaneous abortions: relation to occupation and air pollution by sulfur dioxide, hydrogen sulfide, and carbon disulfide.自然流产的社区研究:与职业以及二氧化硫、硫化氢和二硫化碳造成的空气污染的关系。
Int Arch Occup Environ Health. 1982;51(1):55-63. doi: 10.1007/BF00378410.
2
Spontaneous abortions in an industrialized community in Finland.芬兰一个工业化社区中的自然流产情况。
Am J Public Health. 1983 Jan;73(1):32-7. doi: 10.2105/ajph.73.1.32.
3
Introductory remarks: environmental and endogenous hazards to the female reproductive system.
引言:女性生殖系统面临的环境及内源性危害
Environ Health Perspect. 1981 Apr;38:35-7. doi: 10.1289/ehp.813835.
4
Reproduction and work.繁殖与工作。
Br Med J (Clin Res Ed). 1986 Dec 13;293(6561):1521-2. doi: 10.1136/bmj.293.6561.1521.