Butcher R L, Page R D
Environ Health Perspect. 1981 Apr;38:35-7. doi: 10.1289/ehp.813835.
The toxic action of environmental chemicals on reproduction and the toxiclike effects of ovarian hormones have been shown by numerous investigators. Some toxic effects of environmental chemicals on reproduction are through their action on hormonal secretion. Such effects on the endocrine system could provide additional approaches to investigations of toxicity of compounds. A better understanding of interactions of environmental chemicals with the endocrine system is needed. Therefore, it becomes important for a greater exchange of information and more interaction between toxicologists and endocrinologists.
众多研究人员已证实环境化学物质对生殖的毒性作用以及卵巢激素的类毒性效应。环境化学物质对生殖的某些毒性作用是通过其对激素分泌的作用来实现的。这种对内分泌系统的影响可为化合物毒性的研究提供额外的途径。需要更好地了解环境化学物质与内分泌系统之间的相互作用。因此,毒理学家和内分泌学家之间加强信息交流和更多互动变得很重要。