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中国慢性阻塞性肺疾病负担:基于全球疾病负担研究2021的分析并与美国比较

Burden of Chronic obstructive pulmonary disease in China: an analysis based on the GBD 2021 compared with the United States.

作者信息

Li Rong, Li Yu, Xiong Chan, Gao Wei

机构信息

Acupuncture and massage, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Respiratory and critical care Medicine, The Third Affiliated Hospital of Chengdu University of Traditional Chinese Medicine (West), Chengdu, Sichuan, China.

出版信息

PLoS One. 2025 Apr 17;20(4):e0321470. doi: 10.1371/journal.pone.0321470. eCollection 2025.

Abstract

BACKGROUND

Chronic obstructive pulmonary disease is an important disease affecting physical health worldwide, and the burden of this disease has been growing since 1991 for both China and the US.

OBJECTIVE

To examine the changes in the burden of COPD in both China and the US between 1990-2021.

METHODS

The joinpoint analysis, age-Period-Cohort analysis, decomposition analysis, predictive analysis methods were used to describe prevalence, incidence, death, and disability-adjusted life years for COPD in China and the US.

RESULTS

Compared with China, all four measures of the US COPD burden were higher than they had been in 1990. The burden of COPD increases with age in China. Conversely, in the US, the burden of COPD is getting younger. The epidemiological changes have contributed to an increasing burden of COPD in the US, but have led to a decline in the burden of COPD in China. By 2042, the number of cases in both countries will rise, especially the death rate in the US.

CONCLUSION

The burden of COPD will not rapidly decline in the short term, both China and the US, as well as the global community, must take this disease seriously.

摘要

背景

慢性阻塞性肺疾病是一种影响全球身体健康的重要疾病,自1991年以来,中美两国该疾病的负担一直在增加。

目的

研究1990年至2021年间中美两国慢性阻塞性肺疾病负担的变化。

方法

采用连接点分析、年龄-时期-队列分析、分解分析、预测分析方法描述中美两国慢性阻塞性肺疾病的患病率、发病率、死亡率和伤残调整生命年。

结果

与中国相比,美国慢性阻塞性肺疾病负担的所有四项指标均高于1990年。在中国,慢性阻塞性肺疾病的负担随年龄增长而增加。相反,在美国,慢性阻塞性肺疾病的负担正趋于年轻化。流行病学变化导致美国慢性阻塞性肺疾病负担增加,但在中国却导致了慢性阻塞性肺疾病负担下降。到2042年,两国的病例数都将上升,尤其是美国的死亡率。

结论

慢性阻塞性肺疾病负担在短期内不会迅速下降,中美两国以及国际社会都必须认真对待这种疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2676/12005532/ee307aaecee2/pone.0321470.g001.jpg

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