Darand Mina, Ghorbani Moloud, Ghadiri-Anari Akram, Arabi Vahid, Hosseinzadeh Mahdieh
Prevention of Cardiovascular Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Nutrition, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
BMC Womens Health. 2025 Apr 18;25(1):189. doi: 10.1186/s12905-025-03695-2.
In light of the observed association between nutritional factors and polycystic ovary syndrome (PCOS) in recent decades, the present study was conducted to investigate the association between the consumption of various types of meat and PCOS in Iranian women.
This frequency-matched case-control study included 108 women with newly diagnosed PCOS and 108 age and body-mass-index-matched women without PCOS, as a control group, who were referred to the Yazd Diabetes Clinic and Khatam Clinic between January 2018 and March 2019. The validated 178-item food frequency questionnaire was used to assess the usual dietary intake. Logistic regression analysis was used to estimate the association between meat consumption and PCOS.
The findings of this study showed, the individuals in the third tertile of red meat intake, had higher odds of PCOS in the crude model (Odds Ratio (OR) = 4.29; 95% Confidence Interval (CI), 2.13-8.64; P-value = 0.001) compared with those in the first tertile. These results remained significant after adjustments for energy intake, marital status, physical activity, education, pregnancy history and chronic disease history (OR = 3.87; 95% CI, 1.78-8.40; P-value = 0.001). Higher consumption of red meat increased the risk of PCOS by 3.87 times. Furthermore, higher consumption of processed meats increased the risk of PCOS by 2.15 times (OR = 2.15; 95% CI, 1.05-4.39; P-value and trend = 0.035). We did not find an association between other types of meat consumption and PCOS.
The results of the present study showed that a higher consumption of red and processed meat is associated with a higher risk of PCOS, whereas no significant correlation was found between the consumption of poultry, fish, and organ meat and PCOS. However, more studies are needed to support these findings in the future.
鉴于近几十年来观察到营养因素与多囊卵巢综合征（PCOS）之间存在关联，本研究旨在调查伊朗女性食用各类肉类与PCOS之间的关联。
这项频率匹配的病例对照研究纳入了108例新诊断为PCOS的女性和108例年龄及体重指数匹配的无PCOS女性作为对照组，她们于2018年1月至2019年3月期间被转诊至亚兹德糖尿病诊所和哈塔姆诊所。采用经过验证的178项食物频率问卷评估日常饮食摄入量。采用逻辑回归分析来估计肉类消费与PCOS之间的关联。
本研究结果显示，在未调整模型中，红肉摄入量处于第三个三分位数的个体患PCOS的几率高于第一个三分位数的个体（优势比（OR）=4.29；95%置信区间（CI），2.13 - 8.64；P值=0.001）。在对能量摄入、婚姻状况、身体活动、教育程度、妊娠史和慢性病病史进行调整后，这些结果仍然显著（OR = 3.87；95% CI，1.78 - 8.40；P值=0.001）。红肉摄入量增加使PCOS风险增加3.87倍。此外，加工肉类摄入量增加使PCOS风险增加2.15倍（OR = 2.15；95% CI，1.05 - 4.39；P值及趋势=0.035）。我们未发现食用其他类型肉类与PCOS之间存在关联。
本研究结果表明，较高的红肉和加工肉类消费量与较高的PCOS风险相关，而家禽、鱼类和内脏肉类的消费量与PCOS之间未发现显著相关性。然而，未来还需要更多研究来支持这些发现。
