Weisbach W, Niedner W, Wagner F, Jäger K H
Zentralbl Gynakol. 1985;107(11):664-9.
Clenbuterol (Contraspasmin, Spiropent) was used to treat threatened delivery in a dosage of three times 0.02 mg per day because of its beta-mimetic effects and the halflife time for elimination of 34 hours. We examined the effect of Clenbuterol on the maternal rheobase as a factor to estimate the influence of this drug on neuromuscular structures of maternal organism. After the first oral application of Clenbuterol we found a significant decrease in this value and after second and third application a distinct fluctuation. This fact shows besides the positive beta-mimetic properties the side-effects on the vegetative nerve system and on neuromuscular structures of the female body.
克仑特罗（喘舒平、施博）因其β-拟交感神经作用及34小时的消除半衰期，曾以每日三次、每次0.02毫克的剂量用于治疗先兆流产。我们研究了克仑特罗对母体基强度的影响，以此作为评估该药物对母体机体神经肌肉结构影响的一个因素。首次口服克仑特罗后，我们发现该值显著下降，第二次和第三次用药后出现明显波动。这一事实表明，除了积极的β-拟交感神经特性外，该药物对女性身体的自主神经系统和神经肌肉结构还有副作用。
