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孟加拉国大学生胃食管反流病(GERD)易感性及其相关因素评估:一项横断面研究。

Evaluation of the Susceptibility of Bangladeshi University Students to Gastroesophageal Reflux Disease (GERD) and Its Associated Factors: A Cross-Sectional Study.

作者信息

Hossain Tashfia, Mahmood Ipshita Fariha, Hossain Md Sabbir, Tabassum Nazifa, Shipa Sowkat Jahan, Sarkar Md Raihan

机构信息

School of Pharmacy and Public Health Independent University Dhaka Bangladesh.

Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy University of Dhaka Dhaka Bangladesh.

出版信息

Health Sci Rep. 2025 Apr 16;8(4):e70646. doi: 10.1002/hsr2.70646. eCollection 2025 Apr.

Abstract

BACKGROUND AND AIMS

Gastroesophageal reflux disease (GERD) is a highly prevalent clinical condition all over the world. The study was conducted to determine the GERD prevalence among Bangladeshi university students using the frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) score and to find out what factors are linked to the disease.

METHODS

The study was based on descriptive cross-sectional analysis. After a comprehensive literature review, a questionnaire was developed with some pre-structured options kept in the sociodemographic, dietary, and lifestyle sections along with the FSSG parameters. The tool was disseminated among students of different universities in Bangladesh. After receiving the responses, all the data was analyzed using SPSS software (version 26.0).

RESULTS

After scrutiny, 402 responses of the study participants were subjected to statistical analysis, and among participants, 57.2% ( = 230) were female and 42.8% ( = 172) were male. The GERD prevalence was 45.5% ( = 183), which indicated the FSSG score was more than 8 among 45.5% of the individuals. Logistic regression analysis revealed that eating beyond fullness (OR = 2.859, CI = 1.811-4.515), consumption of painkillers (OR = 2.237, CI = 1.370-3.653), anxiety (OR = 2.349, CI = 1.529-3.611), being stressed (OR = 2.255, CI = 1.456-3.494), quick eating habit (OR = 1.845, CI = 1.240-2.745), poor sleep quality (OR = 1.760, CI = 1.183-2.620), fast food consumption (OR = 1.613, CI = 1.082-2.404), eating sour and spicy food regularly (OR = 1.610, CI = 1.073-2.415), female gender (OR = 1.595, CI = 1.068-2.381), less interval between dinner and sleep (OR = 1.561, CI = 1.020-2.389), being alone most of the time (OR = 1.514, CI = 1.016-2.257), were significantly associated with the occurrence of GERD symptoms.

CONCLUSION

GERD symptoms were seen among a large number of university students. Various sociodemographic, dietary, and lifestyle-related factors had an impact on the disease; these contributing factors should be positively modified to alleviate the burden of GERD symptoms.

摘要

背景与目的

胃食管反流病(GERD)在全球范围内是一种高度普遍的临床病症。本研究旨在使用胃食管反流病症状频率量表(FSSG)评分来确定孟加拉国大学生中GERD的患病率,并找出与该疾病相关的因素。

方法

本研究基于描述性横断面分析。在进行全面的文献综述后,编制了一份问卷,在社会人口统计学、饮食和生活方式部分以及FSSG参数中设置了一些预先设定的选项。该工具在孟加拉国不同大学的学生中进行发放。收到回复后,使用SPSS软件(版本26.0)对所有数据进行分析。

结果

经过仔细审查,对研究参与者的402份回复进行了统计分析,其中57.2%(n = 230)为女性,42.8%(n = 172)为男性。GERD患病率为45.5%(n = 183),这表明45.5%的个体FSSG评分超过8分。逻辑回归分析显示,吃得过饱(OR = 2.859,CI = 1.811 - 4.515)、服用止痛药(OR = 2.237,CI = 1.370 - 3.653)、焦虑(OR = 2.349,CI = 1.529 - 3.611)、压力大(OR = 2.255,CI = 1.456 - 3.494)、进食速度快(OR = 1.845,CI = 1.240 - 2.745)、睡眠质量差(OR = 1.760,CI = 1.183 - 2.620)、食用快餐(OR = 1.613,CI = 1.082 - 2.404)、经常食用酸辣食物(OR = 1.610,CI = 1.073 - 2.415)、女性性别(OR = 1.595,CI = 1.068 - 2.381)、晚餐与睡觉间隔时间短(OR = 1.561,CI = 1.020 - 2.389)、大部分时间独处(OR = 1.514,CI = 1.016 - 2.257),均与GERD症状的发生显著相关。

结论

大量大学生存在GERD症状。各种社会人口统计学、饮食和生活方式相关因素对该疾病有影响;应积极改善这些促成因素,以减轻GERD症状的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b5f/12003919/6ade7d4b44be/HSR2-8-e70646-g001.jpg

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