评估巴基斯坦旁遮普省南部胃食管反流病（GERD）的发病频率及相关风险因素。
Assessing the Frequency and Risk Factors Associated with Gastroesophageal Reflux Disease (GERD) in Southern Punjab, Pakistan.
作者信息
Rasool Muhammad Fawad, Sarwar Rimsha, Arshad Muhammad Subhan, Imran Imran, Saeed Hamid, Majeed Abdul, Akbar Muqarrab, Chaudhry Muhammad Omer, Rehman Anees Ur, Ashraf Waseem, Ahmad Tanveer, Badoghaish Waleed, Alqahtani Faleh
机构信息
Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Department of Pharmacy, Southern Punjab Institute of Health Sciences, Multan, 60000, Pakistan.
出版信息
Risk Manag Healthc Policy. 2021 Nov 12;14:4619-4625. doi: 10.2147/RMHP.S335142. eCollection 2021.
PURPOSE
Gastroesophageal reflux disease (GERD) is a highly prevalent gastrointestinal disorder with modifiable risk factors and it is associated with considerable health and economic burden. The current study was conducted to assess the frequency and risk factors related to GERD in the previously unstudied population of Southern Punjab, Pakistan.
METHODS
A cross-sectional study was conducted for assessing the frequency and risk factors of GERD by using a self-administered questionnaire. The gastroesophageal reflux disease questionnaire (GerdQ) was utilized to detect the presence of the disease.
RESULTS
The study included 308 participants; among them, 55.2% were female and 44.8% were male. The participants diagnosed with GERD (GerdQ score ≥8) were 26.6%. The various risk factors like higher BMI, past disease and smoking history, frequent use of NSAIDs, soft drinks, pickles, and spicy foods were significantly associated with GERD.
CONCLUSION
The present study showed that GERD is prevalent in Southern Punjab and is associated with various modifiable risk factors. The ascendance of GERD can be prevented by public health education and awareness campaigns.
目的
胃食管反流病（GERD）是一种高度常见的胃肠道疾病，具有可改变的风险因素，且与相当大的健康和经济负担相关。本研究旨在评估巴基斯坦旁遮普省南部此前未被研究的人群中与GERD相关的发病率及风险因素。
方法
采用自行填写问卷的方式进行一项横断面研究，以评估GERD的发病率及风险因素。使用胃食管反流病问卷（GerdQ）来检测疾病的存在情况。
结果
该研究纳入了308名参与者；其中，55.2%为女性，44.8%为男性。被诊断为GERD（GerdQ评分≥8）的参与者占26.6%。较高的体重指数、既往病史和吸烟史、频繁使用非甾体抗炎药、软饮料、泡菜和辛辣食物等各种风险因素与GERD显著相关。
结论
本研究表明，GERD在旁遮普省南部普遍存在，且与各种可改变的风险因素相关。通过公共卫生教育和宣传活动可以预防GERD的上升。
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