Geng Lianhua, Qin Yingchun, Gao Yuehua, Zhang Wei
The People's Hospital of DanYang, Danyang Hospital Affiliated to Nantong University, Danyang, 212300, Jiangsu, China.
Department of Nephrology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing, China.
Int Urol Nephrol. 2025 Apr 18. doi: 10.1007/s11255-025-04518-x.
In recent years, inadequate sleep duration has become a prominent concern all over the world, prompting investigations into its potential influences on various health conditions, including kidney disease. This study seeks to explore the association between weekend catch-up sleep (WCS) and kidney disease in American adults.
A cross-sectional study was performed utilizing data from the National Health and Nutrition Examination Surveys (NHANES) spanning the years 2017-2020. The participants included who were 18 years old or older and clearly awareness of their sleep durations on weekdays and weekends. Sleep durations on weekdays and weekends were ascertained through questionnaires, and WCS was determined as the disparity between weekend and weekday sleep durations.
Participants with kidney disease exhibited notable variations in their weekday and weekend sleep durations in comparison to those without. The WCS of more than 2 h, irrespective of comorbidities such as hypertension and diabetes, was significantly linked to a lower prevalence of kidney disease, particularly in individuals who slept 6-8 h on weekdays. Furthermore, it was noted that there exists a non-linear correlation between WCS and the prevalence of kidney disease, with a distinct breakpoint identified at 3.5 h. The WCS of more than 2 h-possibly but not certainly-irrespective of comorbidities such as hypertension and diabetes, was significantly linked to a lower prevalence of kidney disease, particularly in individuals who slept 6-8 h on weekdays.
This research indicates that among adults with insufficient weekday sleep in the United States, participation in WCS, particularly exceeding 2 h is significantly linked to a decreased prevalence of kidney disease. These results offer new perspectives on the connection between sleep patterns and kidney disease, which could inform preventive measures for this prevalent chronic condition.
近年来，睡眠时长不足已成为全球一个突出问题，促使人们对其对包括肾脏疾病在内的各种健康状况的潜在影响展开调查。本研究旨在探讨美国成年人周末补觉（WCS）与肾脏疾病之间的关联。
利用2017年至2020年国家健康与营养检查调查（NHANES）的数据进行了一项横断面研究。参与者为18岁及以上且清楚知晓自己平日和周末睡眠时长的人群。通过问卷调查确定平日和周末的睡眠时长，WCS定义为周末与平日睡眠时长的差值。
与未患肾脏疾病的参与者相比，患肾脏疾病的参与者在平日和周末的睡眠时长存在显著差异。无论是否患有高血压和糖尿病等合并症，WCS超过2小时与较低的肾脏疾病患病率显著相关，尤其是在平日睡眠6 - 8小时的个体中。此外，还注意到WCS与肾脏疾病患病率之间存在非线性关系，在3.5小时处有一个明显的转折点。无论是否患有高血压和糖尿病等合并症，WCS超过2小时（可能但不一定）与较低的肾脏疾病患病率显著相关，尤其是在平日睡眠6 - 8小时的个体中。
本研究表明，在美国平日睡眠不足的成年人中，参与周末补觉，尤其是补觉超过2小时，与较低的肾脏疾病患病率显著相关。这些结果为睡眠模式与肾脏疾病之间的联系提供了新的视角，可为这种常见慢性病的预防措施提供参考。
