沙特阿拉伯利雅得急性冠状动脉综合征患者自我报告结局及心脏症状的性别差异

Gender differences in patient-reported outcomes and cardiac symptoms in patients with acute coronary syndrome in Riyadh, Saudi Arabia.

作者信息

Alosaimi Sultan, Alqarni Abdullah, Alkalifah Turki, Aldaijy Mansor, Alghamdi Nawaf, Altalhah Abdulltaif, Kazi Ambreen, Alharbi Waleed

机构信息

From the College of Medicine (Alosaimi, Alqarni, Alkalifah, Aldaijy, Alghamdi, Altalhah), King Saud University Medical City, King Saud University; From the Deanship of Research Chairs Program (Kazi), King Saud University; from the Department of Family & Community Medicine (Kazi), College of Medicine, King Saud University Medical City; Department of Cardiac Sciences (Alharbi), College of Medicine, King Fahad Cardiac Center, King Saud University Medical City, King Saud University Riyadh, Kingdom of Saudi Arabia.

出版信息

Saudi Med J. 2025 Apr;46(4):388-397. doi: 10.15537/smj.2025.46.20240735.

DOI:10.15537/smj.2025.46.20240735

PMID:40254316

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12010502/

Abstract

OBJECTIVES

To measure the gender differences in patient-reported outcomes and cardiac symptoms in patients with acute coronary syndrome (ACS) at King Khalid University Hospital in Riyadh, Saudi Arabia.

METHODS

A cross-sectional study was conducted on 240 randomly selected ACS patients aged ≥18 years. Data were collected using validated questionnaires, including Patient-reported outcomes measures, the Rose Dyspnea Scale, Patient Health Questionnaire, and Seattle Angina Questionnaire. Multiple linear regression analysis was conducted to identify factors associated with quality of life (QoL).

RESULTS

The study included 60% males and 40% females. Females reported significantly lower global physical health scores (11.62 [±2.49] versus (vs) 13.68 [±2.68], =0.00), higher dyspnea symptoms (2.61 [±1.41] vs 1.55 [±1.51], =0.00), and more physical limitation (43.2 [±31.8] vs 55.19 [±33.96], =0.02). Multiple linear regression analysis showed female gender was associated with a decline in physical health (-0.33 [-2.42, -1.00]), increased dyspnea symptoms (0.30 [0.55, 1.37]), higher depression scores (0.14 [0.004, 0.87]), a decline in SAQ physical activity [-0.19 (-23.68, -2.60)] and summary scores [-0.14 (-11.34, -.04)]. Older age and lower income were also significantly associated with poorer QoL outcomes.

CONCLUSION

Female gender, advanced age, and lower income were associated with worse patient-reported outcomes in ACS patients. Healthcare providers should consider these disparities to improve management strategies and QoL in this population.

摘要

目的

在沙特阿拉伯利雅得的哈立德国王大学医院，测量急性冠状动脉综合征（ACS）患者中患者报告的结局及心脏症状方面的性别差异。

方法

对240名年龄≥18岁的随机选取的ACS患者进行了一项横断面研究。使用经过验证的问卷收集数据，包括患者报告的结局测量、罗斯呼吸困难量表、患者健康问卷和西雅图心绞痛问卷。进行多元线性回归分析以确定与生活质量（QoL）相关的因素。

结果

该研究纳入了60%的男性和40%的女性。女性报告的总体身体健康得分显著更低（11.62[±2.49]对比（vs）13.68[±2.68]，P = 0.00），呼吸困难症状更严重（2.61[±1.41]对比1.55[±1.51]，P = 0.00），身体限制更多（43.2[±31.8]对比55.19[±33.96]，P = 0.02）。多元线性回归分析显示，女性性别与身体健康下降（-0.33[-2.42，-1.00]）、呼吸困难症状增加（0.30[0.55，1.37]）、抑郁得分更高（0.14[0.004，0.87]）、西雅图心绞痛问卷身体活动得分下降[-0.19（-23.68，-2.60）]以及汇总得分下降[-0.14（-11.34，-0.04）]相关。年龄较大和收入较低也与较差的生活质量结局显著相关。