了解沙特阿拉伯癌症患者的生活质量：一项横断面研究的见解。
Understanding the Quality of Life Among Patients With Cancer in Saudi Arabia: Insights From a Cross-Sectional Study.
作者信息
Aljawadi Mohammad H, Alkhudair Nora, Alrasheed Marwan, Alsuhaibani Abdulaziz S, Alotaibi Basil J, Almuqbil Mansour, Alhammad Abdullah M, Arafah Azhar, AlGahtani Farjah H, Rehman Muneeb U
机构信息
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Department of internal Medicine, King Saud University College of Medicine, King Khalid University Hospital, Riyadh, Saudi Arabia.
出版信息
Cancer Control. 2024 Jan-Dec;31:10732748241263013. doi: 10.1177/10732748241263013.
INTRODUCTION
Cancer patients' quality of life (QoL) significantly influences treatment response and mortality rates. Understanding QoL domains among patients with cancer and what affects it can help create interventions that improve QoL and ease patients' experience. This study measures the OoL among patients with cancer and influencing factors.
METHODS
A prospective cross-sectional questionnaire-based study included cancer patients aged >18 currently receiving treatment. The questionnaire collected social and economic data, followed by the validated Arabic version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30). Means and standard deviations for described numeric variables and frequencies and percentages described categorical variables. Analysis of variance, F-tests, and -values were reported.
RESULTS
Among 182 cancer patients, 60% were female. Younger patients exhibited higher QoL in physical and role functioning ( = .016 and .03) and experienced more significant financial impact ( = .0144). Females reported more adverse effects from cancer symptoms, including fatigue, nausea, vomiting, and pain (36.7% vs 25.5%, = .005; 20.6% vs 11.5%, = .0186; 34.7% vs 25.1%, = .0281). Single patients had superior QoL in physical functioning compared to others ( = .0127). Patients traveling long distances were more likely to face adverse financial consequences ( = .007). Asthmatic patients exhibited lower QoL in physical, role, and cognitive functioning (72.3 vs 37.8, = .0147; 76.4 vs 22.2, = .0024; 84.7 vs 44.4, = .0038) and reported increased dyspnea and appetite loss (16 vs 55.6 and 26.1 vs 66.7, both < .05).
CONCLUSION
Factors influencing QoL in Saudi cancer patients include age, marital status, gender, hospital distance, and chronic conditions. Thus emphasizing the necessity for personalized care strategies to enhance outcomes and alleviate the overall burden of cancer care.
引言
癌症患者的生活质量（QoL）对治疗反应和死亡率有显著影响。了解癌症患者的生活质量领域及其影响因素有助于制定改善生活质量并减轻患者痛苦的干预措施。本研究旨在测量癌症患者的生活质量及其影响因素。
方法
一项基于问卷的前瞻性横断面研究纳入了年龄大于18岁且正在接受治疗的癌症患者。问卷收集了社会和经济数据，随后使用经过验证的欧洲癌症研究与治疗组织生活质量问卷（EORTC-QLQ-C30）阿拉伯语版本。报告了所描述数值变量的均值和标准差以及分类变量的频率和百分比。报告了方差分析、F检验和P值。
结果
在182名癌症患者中，60%为女性。较年轻的患者在身体和角色功能方面表现出更高的生活质量（P = 0.016和0.03），并且经历了更显著的经济影响（P = 0.0144）。女性报告癌症症状带来的不良反应更多，包括疲劳、恶心、呕吐和疼痛（36.7%对25.5%，P = 0.005；20.6%对11.5%，P = 0.0186；34.7%对25.1%，P = 0.0281）。单身患者在身体功能方面的生活质量优于其他患者（P = 0.0127）。长途就医的患者更有可能面临不利的经济后果（P = 0.007）。哮喘患者在身体、角色和认知功能方面的生活质量较低（72.3对37.8，P = 0.0147；76.4对22.2，P = 0.0024；84.7对44.4，P = 0.0038），并且报告呼吸困难和食欲减退增加（16对55.6以及26.1对66.7，两者P均<0.05）。
结论
影响沙特癌症患者生活质量的因素包括年龄、婚姻状况、性别、就医距离和慢性病。因此强调了采取个性化护理策略以改善治疗效果并减轻癌症护理总体负担的必要性。
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