Kruis W, Azpiroz F, Phillips S F
Am J Physiol. 1985 Aug;249(2 Pt 1):G264-70. doi: 10.1152/ajpgi.1985.249.2.G264.
Earlier recordings of intraluminal pressure from the terminal ileum and across the ileocolonic sphincter of dogs revealed, in addition to the usual interdigestive and digestive patterns, pressure waves that appeared to have propulsive potential. One of these, which we designated as a "prolonged propagated contraction" (PPC), was a wave of high amplitude; it had a duration much longer than the ileal slow wave and migrated rapidly through the ileum, often into the proximal colon. The other pattern was one of "discrete clustered contractions" (DCC); these were propagated bursts of rhythmic phasic waves, distinct from phase III of the interdigestive myoelectric complex. These migrated through the ileum more rapidly than did phase III. Our aims were to record the electrical and mechanical equivalents of these pressure events using only extraluminal sensors and to evaluate the capacity of these contractions to propel fluids. PPCs and DCCs were recorded by extraluminal strain gauges, and flow was assessed by recovery of a nonabsorbable marker. Phase III of the migrating motor complex propelled fluid through the ileum, but in addition DCCs and, especially, PPCs were able to empty the ileum. These latter contractions have similarities to the ileal "peristaltic rush" described by others, and we believe these waves are an important force for ileal emptying.
早期对犬回肠末端及回结肠括约肌腔内压力的记录显示，除了常见的消化间期和消化期模式外，还存在似乎具有推进潜力的压力波。其中一种，我们将其命名为“延长传播收缩”（PPC），是一种高振幅波；其持续时间比回肠慢波长得多，并迅速通过回肠，常常进入近端结肠。另一种模式是“离散簇状收缩”（DCC）；这些是有节律的阶段性波的传播爆发，与消化间期肌电复合波的第三相不同。它们在回肠中的迁移速度比第三相快。我们的目的是仅使用腔外传感器记录这些压力事件的电和机械等效物，并评估这些收缩推动液体的能力。通过腔外应变仪记录PPC和DCC，并通过回收不可吸收标记物评估流量。移行运动复合波的第三相推动液体通过回肠，但除此之外，DCC，尤其是PPC能够排空回肠。这些后期收缩与其他人描述的回肠“蠕动冲”相似，我们认为这些波是回肠排空的重要力量。
