Chopra Viresh, Davis Graham, Baysan Aylin
Department of Adult Restorative Dentistry, Oman Dental College, Department of Oral Bioengineering, Queen Mary University, Mile End Rd. Bethnal Green, London E1 4NS, UK.
Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, Mile End Rd. Bethnal Green, London E1 4NS, UK.
Materials (Basel). 2021 Dec 29;15(1):229. doi: 10.3390/ma15010229.
The aim of this systematic review is to analyse the effect of physico-chemical properties of calcium silicate-based sealers in comparison to epoxy resin sealers in permanent teeth using a single-cone obturation technique.
The study was conducted according to the guidelines of Cochrane Handbook for Systematic Reviews of Interventions and Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement. Literature search was performed using the PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, DOAJ, Open Gray with no language restrictions until October 2020. Two reviewers assessed the studies for eligibility. Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) was carried out to assess the evidence. Meta-analysis of the pooled data with subgroups was performed using the RevMan software ( < 0.05).
Results from the 28 included studies showed that the mean difference in adaptation to root canal walls (marginal adaptation, interfacial gaps and void volume) for both sealers were non-significant. However, void volume values showed a significant mean difference ( < 0.00001) favouring the calcium silicate-based sealers. The pooled meta-analysis reported statistically significant differences for apical microleakage ( = 0.0007) whilst there were non-significant mean differences for fracture resistance ( = 0.09) and push-out bond strength ( = 0.63). The heterogeneity among the included studies was 97% (I).
Within the limitations of this review, calcium silicate-based sealers demonstrated a similar or superior performance in comparison to resin-based sealers in terms of the physico-chemical properties.
本系统评价的目的是分析采用单锥充填技术时，硅酸钙类封闭剂与环氧树脂封闭剂相比，在恒牙中的物理化学性能影响。
本研究按照Cochrane干预措施系统评价手册和系统评价与Meta分析优先报告项目（PRISMA）声明的指南进行。使用PubMed/MEDLINE、Cochrane对照试验中央注册库、科学网、DOAJ、Open Gray进行文献检索，检索截至2020年10月，无语言限制。两名研究者评估研究的纳入资格。采用推荐分级、评估、制定与评价（GRADE）方法评估证据。使用RevMan软件（<0.05）对汇总数据进行亚组Meta分析。
纳入的28项研究结果显示，两种封闭剂在与根管壁的适应性（边缘适应性、界面间隙和空隙体积）方面的平均差异无统计学意义。然而，空隙体积值显示出有利于硅酸钙类封闭剂的显著平均差异（<0.00001）。汇总的Meta分析报告根尖微渗漏有统计学显著差异（=0.0007），而抗折性（=0.09）和推出粘结强度（=0.63）的平均差异无统计学意义。纳入研究间的异质性为97%（I）。
在本评价的局限性范围内，硅酸钙类封闭剂在物理化学性能方面与树脂类封闭剂相比表现出相似或更优的性能。
