Rosenberg R
Am J Trop Med Hyg. 1985 Jul;34(4):687-91. doi: 10.4269/ajtmh.1985.34.687.
Oocysts of Plasmodium knowlesi developed normally on the gut of the mosquito Anopheles freeborni, rupturing and releasing sporozoites at 10-14 days post-infection. Subsequently, however, sporozoites were never found in this mosquito's salivary glands. Heterologous transplants of whole salivary glands from uninfected An. freeborni and An. dirus, a completely susceptible mosquito, into the abdomens of insects heavily infected with mature oocysts were done. Sporozoites failed to infect An. freeborni glands implanted in An. dirus but did enter An. dirus glands implanted in An. freeborni. These experiments suggest that P. knowlesi sporozoites are unable to recognize An. freeborni glands.
诺氏疟原虫的卵囊在弗氏按蚊的肠道内正常发育,在感染后10 - 14天破裂并释放子孢子。然而,随后在这种蚊子的唾液腺中从未发现子孢子。将未感染的弗氏按蚊和完全易感的迪氏按蚊的整个唾液腺异种移植到大量感染成熟卵囊的昆虫腹部。子孢子未能感染植入迪氏按蚊体内的弗氏按蚊唾液腺,但确实进入了植入弗氏按蚊体内的迪氏按蚊唾液腺。这些实验表明,诺氏疟原虫子孢子无法识别弗氏按蚊的唾液腺。