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[一名在厄瓜多尔亚马逊地区感染的基切瓦族本土儿童的慢性肺吸虫病]

[Chronic pulmonary paragonimiasis in an indigenous Kichwa child infected in the Ecuadorian Amazon].

作者信息

Calvopina Manuel, Guaman-Charco Elías David, Erazo-Coello Jeremmy, Osorio-Pozo Verónica, Cabrera-Aguilar Angelita, Anselmi Mariella

机构信息

One Health Research Group, Facultad de Medicina, Universidad de las Américas, Quito, Ecuador.

Hospital General Marco Vinicio Iza, Ministerio de Salud Pública, Nueva Loja, Sucumbíos, Ecuador.

出版信息

Biomedica. 2025 Mar 28;45(1):17-24. doi: 10.7705/biomedica.7469.

DOI:10.7705/biomedica.7469
PMID:40257943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12105647/
Abstract

Paragonimiasis is caused by the trematode Paragonimus spp. and is considered a foodborne trematodiasis; it is classified as a neglected tropical disease by the World Health Organization, primarily transmitted through the consumption of infected and undercooked freshwater crustaceans. In Ecuador, it predominantly affects tropical regions such as the Coast and the Amazon. We present the case of a ten-year-old Kichwa boy from a rural Amazonian community, diagnosed at the Hospital Pediátrico de Quito. The child presented persistent cough and rusty sputum for four years, with a history of eating crabs. Computed tomography indicated pulmonary parenchymal alterations. The diagnosis of pulmonary paragonimiasis was confirmed via microscopic identification of operculated Paragonimus spp. eggs in the sputum. Treatment with triclabendazole for two days resulted in subsequent negative sputum findings during follow-up examinations. We discuss the possibility of diagnosis in non-endemic regions and the lack of clinical suspicion and laboratory diagnosis in endemic areas. Furthermore, we highlight the shortage of the drugs of choice, triclabendazole, and praziquantel, in Ecuador.

摘要

肺吸虫病由肺吸虫属吸虫引起,被认为是一种食源性吸虫病;世界卫生组织将其列为被忽视的热带病,主要通过食用受感染的未煮熟淡水甲壳类动物传播。在厄瓜多尔,它主要影响沿海和亚马逊等热带地区。我们报告了一名来自亚马逊农村社区的10岁基切瓦男孩的病例,该病例在基多儿科医院被诊断。该儿童持续咳嗽和咳铁锈色痰四年,有吃螃蟹的病史。计算机断层扫描显示肺实质改变。通过显微镜在痰中鉴定出有盖的肺吸虫属虫卵,确诊为肺吸虫病。用三氯苯达唑治疗两天后,后续随访检查痰检结果呈阴性。我们讨论了在非流行地区进行诊断的可能性,以及在流行地区缺乏临床怀疑和实验室诊断的情况。此外,我们强调了厄瓜多尔首选药物三氯苯达唑和吡喹酮短缺的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/0ba0ef741601/2590-7379-bio-45-01-7469-gf4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/6365f5cfc979/2590-7379-bio-45-01-7469-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/036324a401c1/2590-7379-bio-45-01-7469-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/c87ee76d573b/2590-7379-bio-45-01-7469-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/0ba0ef741601/2590-7379-bio-45-01-7469-gf4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/6365f5cfc979/2590-7379-bio-45-01-7469-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/036324a401c1/2590-7379-bio-45-01-7469-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/c87ee76d573b/2590-7379-bio-45-01-7469-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba0/12105647/0ba0ef741601/2590-7379-bio-45-01-7469-gf4.jpg

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本文引用的文献

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Pulmonary paragonimiasis in a child with chronic recurrent wet cough.一名患有慢性反复湿性咳嗽儿童的肺吸虫病
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Case Report: Reemerging Paragonimiasis in Umphang District, Thailand.病例报告:泰国翁庞县复发性并殖吸虫病。
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