Umphang Hospital, Tak, Thailand.
Department of Paediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Am J Trop Med Hyg. 2023 Feb 27;108(4):738-743. doi: 10.4269/ajtmh.22-0708. Print 2023 Apr 5.
Paragonimiasis is a food-born zoonotic parasitosis caused by Paragonimus spp. Six cases of reemerging paragonimiasis within the Karan hill-tribe near the Thai-Myanmar border were evaluated to review clinical manifestations, predisposing factors, and treatment regimens. All patients tested positive for paragonimiasis eggs and presented with an array of symptoms, including chronic cough, hemoptysis, peripheral eosinophilia, and thoracic radiograph abnormalities. All fully recovered after a 2- to 5-day course of 75 to 80 mg/kg/day praziquantel. We conclude that paragonimiasis should be considered during differential diagnoses to promote early treatment and to prevent misdiagnosis of reemerging or sporadic cases. This applies particularly to endemic regions and high-risk groups known to habitually consume raw or undercooked intermediate or paratenic hosts.
并殖吸虫病是一种食源性人畜共患寄生虫病，由并殖属吸虫引起。在泰缅边境附近的卡伦山地部落中，有 6 例复发性并殖吸虫病病例，对其临床表现、易患因素和治疗方案进行了评估。所有患者的并殖吸虫卵检测均呈阳性，并出现一系列症状，包括慢性咳嗽、咯血、外周血嗜酸性粒细胞增多和胸部 X 线异常。所有患者在接受 75 至 80 毫克/千克/天的吡喹酮治疗 2 至 5 天后完全康复。我们得出结论，在鉴别诊断中应考虑并殖吸虫病，以促进早期治疗并防止对复发性或散发性病例的误诊。这尤其适用于已知习惯性食用生的或未煮熟的中间宿主或副宿主的流行地区和高危人群。
