VITACORA - 19问卷和银屑病关节炎影响指数（PsAID）问卷在评估银屑病关节炎对患者生活质量的影响方面同样有效。
The VITACORA- 19 and PsAID questionnaires are equally valid for assessing the impact of psoriatic arthritis on patients' quality of life.
作者信息
Braña Ignacio, Loredo Marta, Torre-Alonso Juan Carlos, Queiro Rubén
机构信息
Rheumatology & ISPA Translational Immunology Division, Hospital Universitario Central de Asturias, Avenida de Roma, S/N 33011, Oviedo, Spain.
Department of Medicine, Facultad de Medicina de La Universidad de Oviedo, Oviedo, Spain.
出版信息
Clin Rheumatol. 2025 Apr 21. doi: 10.1007/s10067-025-07446-4.
BACKGROUND AND AIMS
Health-related quality of life (HRQoL) is an often-underestimated aspect in psoriatic arthritis (PsA). We aimed to compare the VITACORA-19 and PsAID (Psoriatic Arthritis Impact of Disease) questionnaires to assess QoL in routine PsA management.
METHODS
Cross-sectional analysis of a randomly selected PsA population. Disease activity was estimated using the DAPSA (Disease Activity score for PsA) index and HRQoL using the VITACORA-19 and PsAID. The construct validity of VITACORA-19 was analysed (Pearson correlation and ROC curves).
RESULTS
Forty-five patients were included, 24 men and 21 women, mean age 55 ± 13 years, mean disease duration 8.2 ± 6.1 years. Most patients showed adequate disease control, median DAPSA 11.3 (IQR: 8.0-19.3), median PsAID 2.7 (IQR: 1.1-5.0). VITACORA-19 scores ranged from 6 to 94. The correlation between VITACORA-19 and PsAID was high, r: -0.7 (95%CI: -0.84 to -0.46), p < 0.0001. A VITACORA-19 score in the range of 6-29 corresponded to high DAPSA disease activity, a range of 30-44 corresponded to moderate DAPSA activity and a range of 45-95 corresponded to low DAPSA activity. The cut-off for an acceptable symptomatic state (PsAID < 4) corresponded to a VITACORA-19 score ≥ 66 with an area under the ROC curve of 0.85 (95%CI: 0.71-0.98).
CONCLUSIONS
This is the first study comparing the VITACORA-19 and PsAID questionnaires. Either of the two questionnaires could be used to assess HRQoL in PsA. For the first time, VITACORA-19 thresholds are defined that identify the different DAPSA activity categories. A VITACORA-19 score ≥ 66 could be an appropriate treatment target. Key Points • Health-related quality of life (HRQoL) is an often-underestimated aspect in psoriatic arthritis (PsA). • The PsAID and VITACORA-19 questionnaires offer similar performance for assessing HRQoL in PsA. • A VITACORA-19 ≥ 66 identifies the low disease impact state according to the PsAID. • VITACORA-19 thresholds identifying DAPSA categories are reported.
背景与目的
健康相关生活质量（HRQoL）在银屑病关节炎（PsA）中常常被低估。我们旨在比较VITACORA - 19问卷和银屑病关节炎疾病影响问卷（PsAID），以评估PsA常规管理中的生活质量。
方法
对随机选取的PsA患者群体进行横断面分析。使用银屑病关节炎疾病活动评分（DAPSA）指数评估疾病活动度，使用VITACORA - 19问卷和PsAID评估HRQoL。分析VITACORA - 19的结构效度（Pearson相关性和ROC曲线）。
结果
纳入45例患者，其中男性24例，女性21例，平均年龄55±13岁，平均病程8.2±6.1年。大多数患者疾病控制良好，DAPSA中位数为11.3（四分位间距：8.0 - 19.3），PsAID中位数为2.7（四分位间距：1.1 - 5.0）。VITACORA - 19评分范围为6至94。VITACORA - 19与PsAID之间的相关性较高，r： - 0.7（95%置信区间： - 0.84至 - 0.46），p < 0.0001。VITACORA - 19评分在6 - 29范围内对应高DAPSA疾病活动度，30 - 44范围内对应中度DAPSA活动度，45 - 95范围内对应低DAPSA活动度。可接受症状状态（PsAID < 4）的截断值对应VITACORA - 19评分≥66，ROC曲线下面积为0.85（95%置信区间：0.71 - 0.98）。
结论
这是第一项比较VITACORA - 19问卷和PsAID问卷的研究。这两种问卷均可用于评估PsA中的HRQoL。首次定义了VITACORA - 19阈值，以识别不同的DAPSA活动类别。VITACORA - 19评分≥66可能是一个合适的治疗目标。要点 • 健康相关生活质量（HRQoL）在银屑病关节炎（PsA）中常常被低估。 • PsAID和VITACORA - 19问卷在评估PsA中的HRQoL方面表现相似。 • 根据PsAID，VITACORA - 19≥66可识别低疾病影响状态。 • 报告了识别DAPSA类别的VITACORA - 19阈值。
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