Manzke Naiana E, Gormley Alexa R, Kim Young Ihn, Parnsen Wanpuech, Kim Sung Woo
Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA.
Anim Sci J. 2025 Jan-Dec;96(1):e70056. doi: 10.1111/asj.70056.
This study aimed to investigate the efficacy of β-glucan from microalgae (Algamune, Algal Scientific, Plymouth, MI, USA) on the intestinal health and growth of nursery pigs. One hundred sixty nursery pigs (6.0 ± 1.6 kg BW) were assigned to four treatments arranged in a 2 × 2 factor: antibiotic use and β-glucan supplementation (0.02% Algamune). Diets were fed for 5 weeks, at which eight pigs from each treatment were selected for tissue sample collection. During the overall experimental period, antibiotics improved (p < 0.05) ADG and G:F. In Week 5, β-glucan supplementation increased (p < 0.05) the ADG of pigs without antibiotics, whereas β-glucan supplementation had no effect in pigs with antibiotics. In Phase 3, β-glucan supplementation tended to increase (p = 0.061) ADFI of pigs without antibiotics, whereas β-glucan supplementation had no effect in pigs with antibiotics. Both antibiotics and β-glucan increased (p < 0.05) villus height in the duodenum. Supplementation of β-glucan reduced (p < 0.05) IgA in the jejunum and tended to reduce (p = 0.053) IgA in the ileum. In conclusion, β-glucan from microalgae may encourage growth and feed intake of nursery pigs by improving intestinal health when antibiotics are not used in the diets.
本研究旨在探讨微藻来源的β-葡聚糖（Algamune，美国密歇根州普利茅斯市藻类科学公司）对保育猪肠道健康和生长的影响。160头保育猪（体重6.0±1.6千克）被分配到按2×2因子排列的四种处理组中：抗生素使用情况和β-葡聚糖添加量（0.02% Algamune）。日粮饲喂5周，在此期间，从每个处理组中挑选8头猪进行组织样本采集。在整个实验期间，抗生素提高了（p<0.05）平均日增重（ADG）和料重比（G:F）。在第5周，添加β-葡聚糖提高了（p<0.05）未使用抗生素的猪的ADG，而添加β-葡聚糖对使用抗生素的猪没有影响。在第3阶段，添加β-葡聚糖使未使用抗生素的猪的平均日采食量（ADFI）有增加趋势（p=0.061），而添加β-葡聚糖对使用抗生素的猪没有影响。抗生素和β-葡聚糖均增加了（p<0.05）十二指肠绒毛高度。添加β-葡聚糖降低了（p<0.05）空肠中的免疫球蛋白A（IgA），并使回肠中的IgA有降低趋势（p=0.053）。总之，当日粮中不使用抗生素时，微藻来源的β-葡聚糖可能通过改善肠道健康来促进保育猪的生长和采食量。
