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基于抑郁和焦虑对腕管综合征术前患者进行亚型探索:两步聚类分析

Exploring Subtypes Based on Depression and Anxiety in Preoperative Patients With Carpal Tunnel Syndrome: A Two-Step Cluster Analysis.

作者信息

Yoshida Akihito, Iwatsuki Katsuyuki, Shinohara Takaaki, Hirata Hitoshi

机构信息

Department of Integrated Health Sciences, Graduate School of Medicine, Nagoya University, Nagoya City, JPN.

Department of Hand Surgery, Graduate School of Medicine, Nagoya University, Nagoya City, JPN.

出版信息

Cureus. 2025 Mar 20;17(3):e80928. doi: 10.7759/cureus.80928. eCollection 2025 Mar.

DOI:10.7759/cureus.80928
PMID:40260370
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12010026/
Abstract

Background Although a growing body of literature supports the importance of depression and anxiety, the assessment of these modifiable factors has not been considered in recent clinical practice guidelines for patients with carpal tunnel syndrome (CTS). This study aimed to classify patients with CTS into preoperative subgroups using cluster analysis based on the Japanese versions of the Self-Rating Depression Scale (SDS) and Pain Anxiety Symptom Scale-20 (PASS-20). Outcome measures were also compared for each cluster. Methods Data from 65 patients with CTS were analyzed. The SDS and PASS-20 psychological parameters were grouped using the K-means cluster method, according to Ward's method. Sociodemographic, disease-related, physical, psychological, and disability outcomes were compared between the clusters. Results A three-cluster solution, which categorized patients into "psychologically normal," "only depression," and "psychologically impaired" clusters, was selected. Upper extremity disability in the "psychologically impaired" cluster was more severe compared to that in other clusters. Conclusions We provided evidence for the detection of depression and anxiety in patients with CTS at a preoperative period.

摘要

背景 尽管越来越多的文献支持抑郁和焦虑的重要性,但在最近关于腕管综合征(CTS)患者的临床实践指南中,并未考虑对这些可改变因素进行评估。本研究旨在基于自评抑郁量表(SDS)和疼痛焦虑症状量表-20(PASS-20)的日语版本,使用聚类分析将CTS患者术前分为不同亚组。还对每个聚类的结果指标进行了比较。方法 分析了65例CTS患者的数据。根据沃德方法,使用K均值聚类法对SDS和PASS-20心理参数进行分组。比较了各聚类之间的社会人口统计学、疾病相关、身体、心理和残疾结局。结果 选择了一种将患者分为“心理正常”“仅抑郁”和“心理受损”聚类的三聚类解决方案。与其他聚类相比,“心理受损”聚类中的上肢残疾更为严重。结论 我们为术前检测CTS患者的抑郁和焦虑提供了证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e270/12010026/67cb1e5e0e3f/cureus-0017-00000080928-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e270/12010026/5464d3b8b38f/cureus-0017-00000080928-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e270/12010026/4d9791efd7e7/cureus-0017-00000080928-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e270/12010026/67cb1e5e0e3f/cureus-0017-00000080928-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e270/12010026/5464d3b8b38f/cureus-0017-00000080928-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e270/12010026/4d9791efd7e7/cureus-0017-00000080928-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e270/12010026/67cb1e5e0e3f/cureus-0017-00000080928-i03.jpg

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本文引用的文献

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Effectiveness of adding pain neuroscience education to telerehabilitation in patients with carpal tunnel syndrome: A randomized controlled trial.远程康复中加入疼痛神经科学教育对腕管综合征患者的疗效:一项随机对照试验。
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Statistical power for cluster analysis.聚类分析的统计功效。
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Effects of Cognitive and Mental Health Factors on the Outcomes Following Carpal Tunnel Release: A Systematic Review and Meta-analysis.认知和心理健康因素对腕管松解术后结果的影响:系统评价和荟萃分析。
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Atrial fibrillation, quality of life and distress: a cluster analysis of cognitive and behavioural responses.心房颤动、生活质量和困扰:认知和行为反应的聚类分析。
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The long-term effect of neurodynamics vs exercise therapy on pain and function in people with carpal tunnel syndrome: A randomized parallel-group clinical trial.神经动力学与运动疗法治疗腕管综合征患者疼痛和功能的长期效果:一项随机平行组临床试验。
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