McCrone Jenna C, Pignanelli Christopher, Lydiate Gavin C, Grigore Monica M, Turetskiy Katrin, Robertson Alexa A, Parris Regan E J, Bisset-Cavallin Ella M, Burr Jamie F
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
Physiol Rep. 2025 Apr;13(8):e70343. doi: 10.14814/phy2.70343.
Blood flow restriction (BFR) training has emerged as a novel modality with clinical potential. However, BFR increases perceived effort and pain, highlighting the need to identify factors influencing perceptual responses to optimize its practical application. Hypohydration similarly increases discomfort during exercise or painful stimuli, but whether this interacts with BFR is unknown. The purpose of the study was to determine if hydration affects the perceptual response to BFR exercise. Of the 34 participants recruited, 17 (7 females) completed two BFR exercise bouts: (1) Hydrated (regular fluid intake) and (2) Hypohydrated (24 h fluid restriction). Rating of perceived exertion (RPE) and leg pain were recorded throughout. With hypohydration, urine specific gravity increased (Hydrated = 1.01 ± 0.009, vs. Hypohydrated = 1.025 ± 0.002, p < 0.0001), body mass decreased (-2.3 ± 0.7%, p < 0.0001), and plasma volume decreased (-7.0 ± 3.4%, p < 0.0001). Similar RPE and leg pain were reported during BFR exercise (RPE: 10.6 ± 0.9, vs. 11.1 ± 0.9, p = 0.054, leg pain: 3.5 ± 1.1, vs. 3.8 ± 1.2, p = 0.2). Similarly, during the rest periods, there was a minimal effect for RPE (9.1 ± 1, vs. 9.5 ± 1.3, p = 0.1) and leg pain (3.1 ± 1.5, vs. 3.6 ± 1.8, p = 0.09). Preliminary analyses show minimal sex differences in perceptual responses, with hydration status changes unrelated to BFR perception. Thus, hydration status has little impact on perceptual responses to BFR exercise.
血流限制（BFR）训练已成为一种具有临床潜力的新型训练方式。然而，BFR会增加主观用力感和疼痛感，这凸显了识别影响感知反应的因素以优化其实际应用的必要性。脱水同样会增加运动或疼痛刺激期间的不适感，但这是否与BFR相互作用尚不清楚。本研究的目的是确定水合状态是否会影响对BFR运动的感知反应。在招募的34名参与者中，17名（7名女性）完成了两组BFR运动：（1）水合状态良好（正常液体摄入）和（2）脱水状态（24小时液体限制）。全程记录主观用力程度（RPE）和腿部疼痛情况。脱水状态下，尿比重升高（水合状态良好组=1.01±0.009，脱水状态组=1.025±0.002，p<0.0001），体重下降（-2.3±0.7%，p<0.0001），血浆量下降（-7.0±3.4%，p<0.0001）。在BFR运动期间，两组报告的RPE和腿部疼痛情况相似（RPE：10.6±0.9，对比11.1±0.9，p=0.054；腿部疼痛：3.5±1.1，对比3.8±1.2，p=0.2）。同样，在休息期间，RPE（9.1±1，对比9.5±1.3，p=0.1）和腿部疼痛（3.1±1.5，对比3.6±1.8，p=0.09）的影响也很小。初步分析表明，在感知反应方面性别差异极小，水合状态变化与对BFR的感知无关。因此，水合状态对BFR运动的感知反应影响很小。
