Zhang Lin, Wen Jingli, Yuan Ling, Yan Youde, Zhang Zhenjiang, Li Kai, Tang Zuoling
Department of Infectious Diseases, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, Jiangsu, China.
Sci Rep. 2025 Apr 22;15(1):13893. doi: 10.1038/s41598-025-98515-w.
This study aims to assess the levels of anxiety and depression among healthcare workers two years post COVID-19 infection and to validate the reliability and validity of the PHQ-9 and GAD-7 scales in this population. This cross-sectional study was conducted in June 2024 using a simple random sampling approach to survey healthcare institution workers. A total of 1038 valid samples were collected, and anxiety and depression levels were assessed using the PHQ-9 and GAD-7 scales. Participants included healthcare workers such as doctors, nurses, administrative staff, and students. Data analysis included descriptive statistics, correlation analysis, univariate, and multivariate analyses to explore the effects of variables such as occupation and gender on anxiety and depression. Long COVID was reported in 50.8% of participants. Occupational categories significantly influenced anxiety and depression levels: compared to students (reference group), doctors, nurses, and administrative staff exhibited significantly lower scores. Non-long COVID participants showed significantly lower anxiety and depression scores than those with long COVID. Additionally, the PHQ-9 and GAD-7 scales demonstrated high reliability and validity among COVID-19 population. Two years after COVID-19 infection, anxiety and depression levels among healthcare institution workers remain significantly influenced by occupational category and long COVID status. For healthcare workers, particularly those with long COVID and student groups, policymakers and healthcare administrators should consider optimizing mental health support systems. This includes implementing regular mental health screenings, providing personalized psychological interventions, offering counseling services, reducing work-related stress, and promoting the use of mental health assessment tools to improve the psychological well-being of this population.
本研究旨在评估医护人员在感染新冠病毒两年后的焦虑和抑郁水平,并验证PHQ-9和GAD-7量表在该人群中的信效度。这项横断面研究于2024年6月进行,采用简单随机抽样方法对医疗机构工作人员进行调查。共收集了1038份有效样本,使用PHQ-9和GAD-7量表评估焦虑和抑郁水平。参与者包括医生、护士、行政人员和学生等医护人员。数据分析包括描述性统计、相关性分析、单变量和多变量分析,以探讨职业和性别等变量对焦虑和抑郁的影响。50.8%的参与者报告有新冠后遗症。职业类别对焦虑和抑郁水平有显著影响:与学生(参照组)相比,医生、护士和行政人员的得分显著更低。无新冠后遗症的参与者的焦虑和抑郁得分显著低于有新冠后遗症的参与者。此外,PHQ-9和GAD-7量表在新冠病毒感染人群中显示出高信效度。新冠病毒感染两年后,医疗机构工作人员的焦虑和抑郁水平仍受到职业类别和新冠后遗症状态的显著影响。对于医护人员,特别是那些有新冠后遗症的人员和学生群体,政策制定者和医疗管理人员应考虑优化心理健康支持系统。这包括开展定期心理健康筛查、提供个性化心理干预、提供咨询服务、减轻工作相关压力,以及推广使用心理健康评估工具,以改善该人群的心理健康状况。