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推测感染西尼罗河病毒后出现的非典型单侧多灶性脉络膜炎和视网膜血管炎。

Atypical Unilateral Multifocal Choroiditis and Retinal Vasculitis Following Presumed West Nile Virus Infection.

作者信息

Carey Noah L, Tracey Breanna M, Matsyaraja Tejaswini, Trese Matthew, Randhawa Sandeep, Purt Boonkit, Kodati Shilpa

机构信息

Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.

Associated Retinal Consultants, Novi, Michigan, USA.

出版信息

Ocul Immunol Inflamm. 2025 Apr 23:1-4. doi: 10.1080/09273948.2025.2495829.

DOI:10.1080/09273948.2025.2495829
PMID:40267347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12353507/
Abstract

PURPOSE

We report a case of an atypical multifocal choroiditis with retinal vasculitis associated with positive West Nile serology.

METHODS

Retrospective case report.

RESULTS

A healthy 18-year-old man presented with floaters in the left eye that started while backpacking in Wyoming. Examination and testing revealed numerous chorioretinal lesions in the left eye, as well as retinal vasculitis and evidence of branch retinal vein occlusion. Serology was positive for West Nile Virus.

CONCLUSION

West Nile virus may be a trigger for development of multifocal choroiditis in susceptible individuals.

摘要

目的

我们报告一例非典型多灶性脉络膜炎合并视网膜血管炎且西尼罗河血清学呈阳性的病例。

方法

回顾性病例报告。

结果

一名18岁健康男性,在怀俄明州背包旅行时左眼开始出现飞蚊症。检查和检测发现左眼有大量脉络膜视网膜病变,以及视网膜血管炎和视网膜分支静脉阻塞的迹象。西尼罗河病毒血清学检测呈阳性。

结论

西尼罗河病毒可能是易感个体发生多灶性脉络膜炎的诱因。

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本文引用的文献

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Eur J Ophthalmol. 2025 May;35(3):844-855. doi: 10.1177/11206721241304150. Epub 2024 Dec 11.
2
Clinical course of choroidal neovascular membrane in West Nile virus chorioretinitis: a case report.西尼罗河病毒视网膜炎脉络膜新生血管膜的临床病程:一例报告。
J Med Case Rep. 2021 Apr 19;15(1):206. doi: 10.1186/s13256-021-02700-0.
3
Ocular Manifestations of West Nile Virus.西尼罗河病毒的眼部表现
Vaccines (Basel). 2020 Nov 2;8(4):641. doi: 10.3390/vaccines8040641.
4
An unusual case of unilateral chorioretinitis and blind spot enlargement associated with asymptomatic West Nile virus infection.一例与无症状西尼罗河病毒感染相关的单侧脉络膜视网膜炎及盲点扩大的罕见病例。
Am J Ophthalmol Case Rep. 2020 Apr 23;18:100723. doi: 10.1016/j.ajoc.2020.100723. eCollection 2020 Jun.
5
Epidemiology of West Nile Virus in the United States: Implications for Arbovirology and Public Health.美国西尼罗河病毒的流行病学:对虫媒病毒学和公共卫生的启示。
J Med Entomol. 2019 Oct 28;56(6):1456-1462. doi: 10.1093/jme/tjz085.
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Reactivation West Nile virus infection-related chorioretinitis.西尼罗河病毒感染相关脉络膜视网膜炎的再激活
Semin Ophthalmol. 2012 May-Jul;27(3-4):43-5. doi: 10.3109/08820538.2011.631512.
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Br J Ophthalmol. 2010 Jan;94(1):137-9. doi: 10.1136/bjo.2009.159293.
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Epidemiol Infect. 2006 Dec;134(6):1325-32. doi: 10.1017/S0950268806006339. Epub 2006 May 4.
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