Beardsley Robert, McCannel Colin
Jules Stein Eye Institute, UCLA Department of Ophthalmology, Los Angeles, CA 90095, USA.
Semin Ophthalmol. 2012 May-Jul;27(3-4):43-5. doi: 10.3109/08820538.2011.631512.
West Nile Virus is a relatively uncommon infection that can involve retinal and choroidal inflammation leading to photopsias, photophobia, and orbital pain. The diagnosis is made by clinical history, serology, and characteristic funduscopic exam and fluorescein angiography findings. Treatment involves primarily supportive care as there are no known effective anti-viral agents. Visual recovery is usually full. Here we present a case of West Nile Virus Infection Related chorioretinitis that demonstrated active linear chorioretinal lesions approximately one year after the initial infection was diagnosed and treated. The patient noted new onset blurry vision and floaters for two weeks prior to presentation. Antibody titers to West Nile Virus increased from baseline levels indicating active infection. This represents the first case of reactivation West Nile Virus Infection Related chorioretinitis that has been documented.
西尼罗河病毒是一种相对罕见的感染，可累及视网膜和脉络膜炎症，导致视幻症、畏光和眼眶疼痛。诊断通过临床病史、血清学以及特征性的眼底检查和荧光素血管造影结果来做出。由于没有已知有效的抗病毒药物，治疗主要包括支持性护理。视力通常能完全恢复。在此我们报告一例西尼罗河病毒感染相关性脉络膜视网膜炎病例，该病例在最初感染被诊断和治疗后约一年出现了活动性线性脉络膜视网膜病变。患者在就诊前两周出现新发视物模糊和飞蚊症。针对西尼罗河病毒的抗体滴度从基线水平升高，表明存在活动性感染。这是有记录的首例西尼罗河病毒感染相关性脉络膜视网膜炎再激活病例。
