Manschreck T C, Maher B A, Waller N G, Ames D, Latham C A
Biol Psychiatry. 1985 Sep;20(9):990-1002. doi: 10.1016/0006-3223(85)90197-0.
A laboratory measure of synchronization was used to assess the differential ability of schizophrenics, affectives, and normal controls to take advantage of stimulus predictability. It was hypothesized that (1) schizophrenics will perform on this task in a way that distinguishes them from other groups, (2) clinically observed motor anomalies will be associated with deficient motor synchrony, and (3) deficient motor synchrony will be associated with more severe clinical ratings of thought disorder. Twenty-one schizophrenic, 8 affective, and 16 normal controls were studied. The results were consistent with the hypotheses; schizophrenic subjects had distinctive performance patterns, especially at 40 bpm, which was associated with both motor and thinking disturbance. The authors discuss additional analyses that suggest that deficient motor synchrony is associated with negative symptoms, certain ward behaviors, and not with demographic variables, and that among unmedicated schizophrenic subjects, the performance patterns are worse.
采用一种同步性的实验室测量方法来评估精神分裂症患者、情感障碍患者和正常对照组利用刺激可预测性的差异能力。研究假设如下：（1）精神分裂症患者在这项任务中的表现将使其与其他组有所区别；（2）临床观察到的运动异常将与运动同步性不足相关；（3）运动同步性不足将与思维障碍的更严重临床评分相关。对21名精神分裂症患者、8名情感障碍患者和16名正常对照组进行了研究。结果与假设一致；精神分裂症患者有独特的表现模式，尤其是在每分钟40次心跳时，这与运动和思维障碍都有关。作者讨论了进一步的分析，这些分析表明运动同步性不足与阴性症状、某些病房行为相关，而与人口统计学变量无关，并且在未服药的精神分裂症患者中，表现模式更差。
