O Leary Fiona, Coffey Niamh, Burke Francis M, Roberts Anthony, Kirwan Laura, O Regan Paul, Plant Barry, Hayes Martina
Clinical Fellow in Restorative Dentistry, Cork University Dental School and Hospital, Wilton, Cork, Ireland.
Consultant in Restorative Dentistry, Cork University Dental School and Hospital, Wilton, Cork, Ireland.
Br Dent J. 2025 Apr;238(8):648-654. doi: 10.1038/s41415-024-8269-8. Epub 2025 Apr 25.
Objectives To measure past dental caries experience in people with cystic fibrosis and to compare the results with a control group of people without cystic fibrosis.Methods A cross-sectional study of 92 adults with cystic fibrosis and 92 adults without cystic fibrosis was undertaken in Cork University Dental School and Hospital. The median age for study group and control group participants was 31 years and 27 years, respectively. All participants completed a detailed questionnaire before undergoing a clinical examination that recorded demographic, social and oral health variables. Caries was recorded using the Decayed, Missing and Filled Teeth (DMFT) index. All data were statistically analysed using the Wilcoxon rank-sum test, chi-squared test and Fisher's test. Negative binomial models were also used to analyse data.Results The study group had a higher mean DMFT score compared to the control group (6.52, 0.99, 0.41, 3.89 versus 5.33, 0.18, 0.11, 3.68). While the study group had a higher DMFT, the only component that was statistically significant between the groups was the Decayed Teeth component (p <0.001).Conclusion In this study, the cohort of people with cystic fibrosis had more caries than people without cystic fibrosis. Further research is required to establish if underlying systemic conditions, social and behavioural factors, or a combination of the aforementioned are responsible for a higher caries experience in this study group.
目的 测量囊性纤维化患者过去的龋齿经历,并将结果与非囊性纤维化对照组进行比较。方法 在科克大学牙科学院和医院对92名成年囊性纤维化患者和92名成年非囊性纤维化患者进行了一项横断面研究。研究组和对照组参与者的年龄中位数分别为31岁和27岁。所有参与者在接受临床检查前都完成了一份详细的问卷,该问卷记录了人口统计学、社会和口腔健康变量。使用龋失补牙指数(DMFT)记录龋齿情况。所有数据均采用Wilcoxon秩和检验、卡方检验和Fisher检验进行统计学分析。还使用负二项式模型分析数据。结果 研究组的平均DMFT得分高于对照组(6.52、0.99、0.41、3.89对比5.33、0.18、0.11、3.68)。虽然研究组的DMFT较高,但两组之间唯一具有统计学意义的成分是龋齿成分(p<0.001)。结论 在本研究中,囊性纤维化患者队列的龋齿比非囊性纤维化患者更多。需要进一步研究以确定潜在的全身状况、社会和行为因素,或上述因素的组合是否是该研究组龋齿经历较多的原因。