Urasa F M, Wendelaar Bonga S E
Cell Tissue Res. 1985;241(1):219-27. doi: 10.1007/BF00214644.
The corpuscles of Stannius (CS) of the cichlid Oreochromis mossambicus (formerly Sarotherodon mossambicus) were studied in relation to sexual maturation and plasma calcium levels. After sexual maturation, the CS are enlarged in female fish, because of an increase in size and number of the type-1 cells. During the ovarian cycle, the size of the CS increases in parallel with the growth of the ovaries. Concurrently, plasma total calcium increases markedly until spawning. This increase is mainly accounted for by calcium bound to proteins (vitellogenins), but the ultrafiltrable calcium fraction is also slightly higher than in males. Ovariectomy is followed by a reduction in the size of the CS, mainly a result of involution of the type-1 cells, and by a reduction in plasma calcium to levels typical for males. Gonadectomy in males does not affect size or ultrastructure of the CS, or plasma calcium levels. Since the type-1 cells of the CS are the presumptive source of a hypocalcemic hormone, we conclude that activation of the CS during the female reproductive cycle is a response to elevated calcium levels that accompany ovarian maturation. We suggest that the CS respond in particular to the elevated ultrafiltrable or ionic calcium levels.
研究了莫桑比克罗非鱼（原名莫桑比克口孵非鲫）的斯坦尼斯小体（CS）与性成熟及血浆钙水平的关系。性成熟后，雌性鱼类的CS会增大，这是由于1型细胞的大小和数量增加。在卵巢周期中，CS的大小随着卵巢的生长而平行增加。同时，血浆总钙在产卵前显著增加。这种增加主要是由与蛋白质（卵黄生成素）结合的钙引起的，但超滤性钙部分也略高于雄性。卵巢切除术后，CS的大小会减小，这主要是1型细胞退化的结果，同时血浆钙会降至雄性的典型水平。雄性去势不会影响CS的大小、超微结构或血浆钙水平。由于CS的1型细胞是降钙素的推测来源，我们得出结论，雌性生殖周期中CS的激活是对卵巢成熟伴随的钙水平升高的一种反应。我们认为，CS特别对超滤性或离子钙水平的升高做出反应。
