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在斯氏小体的鳗鱼小体中对一种哺乳动物甲状旁腺样激素进行免疫细胞化学检测。

Immunocytochemical detection in eel corpuscles of Stannius of a mammalian parathyroid-like hormone.

作者信息

Lopez E, Tisserand-Jochem E M, Eyquem A, Milet C, Hillyard C, Lallier F, Vidal B, Mac Intyre I

出版信息

Gen Comp Endocrinol. 1984 Jan;53(1):28-36. doi: 10.1016/0016-6480(84)90221-1.

DOI:10.1016/0016-6480(84)90221-1
PMID:6370787
Abstract

Stannius corpuscles of the eel synthesize and secrete a mammalian parathyroid-like hormone called parathyrin of CS (PCS). PCS has been localized in the cytoplasm of all cells in the corpuscles, detection being by indirect immunofluorescence with an antiserum anti-1-84 bovine hormone (PTH). The specificity of the reaction was demonstrated by inhibition of the fluorescent staining with 1-84 bovine PTH and the active fragment 1-34 of human PTH. Variations of the cellular localization of the PCS or a complete depletion of the hormonal content, in all cells, were observed in eels made hypercalcemic by Ca overloading. The secretory activity of the two types of CS cells may be regulated by the plasma Ca2+ concentration.

摘要

鳗鱼的斯坦尼小体合成并分泌一种名为CS甲状旁腺素（PCS）的哺乳动物甲状旁腺样激素。PCS已定位在小体所有细胞的细胞质中，通过用抗1-84牛激素（PTH）抗血清进行间接免疫荧光检测。用1-84牛PTH和人PTH的活性片段1-34抑制荧光染色，证明了反应的特异性。在因钙超载而血钙过高的鳗鱼中，观察到PCS细胞定位的变化或所有细胞中激素含量的完全耗尽。两种类型的CS细胞的分泌活性可能受血浆Ca2+浓度调节。

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1
Immunocytochemical detection in eel corpuscles of Stannius of a mammalian parathyroid-like hormone.在斯氏小体的鳗鱼小体中对一种哺乳动物甲状旁腺样激素进行免疫细胞化学检测。
Gen Comp Endocrinol. 1984 Jan;53(1):28-36. doi: 10.1016/0016-6480(84)90221-1.
2
[Immunocytochemical detection in Stannius corpuscles of the eel (Anguilla anguilla L.) of a hormone similar to the mammalian parathyroid hormone].[在鳗鱼（欧洲鳗鲡）的斯坦尼斯小体中对一种类似于哺乳动物甲状旁腺激素的激素进行免疫细胞化学检测]
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Co-localization and secretion of parathyrin of Stannius corpuscles (immunoreactive parathyroid hormone) and of secretory glycoproteins including secretory protein-I in the European eel (Anguilla anguilla L.).欧洲鳗鲡（Anguilla anguilla L.）中斯坦尼斯小体的甲状旁腺素（免疫反应性甲状旁腺激素）与包括分泌蛋白-I在内的分泌性糖蛋白的共定位和分泌。
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Partial purification of parathyrin from the corpuscles of Stannius (PCS) of the eel (Anguilla anguilla, L.).从鳗鱼（欧洲鳗鲡，L.）的斯坦尼斯小体（PCS）中部分纯化甲状旁腺素。
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[Are Stannius corpuscles the parathyroid glands of teleost fishes? Ultrastructural, cytologic and immunocytochemical arguments].[斯坦尼氏小体是硬骨鱼类的甲状旁腺吗？超微结构、细胞学及免疫细胞化学证据]
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[In vitro translation of RNA extracted from corpuscules of Stannius of the eel (Anguilla anguilla); identification of the precursor of parathyrin in the corpuscules of Stannius (PCS)].[从鳗鱼（欧洲鳗鲡）斯坦尼斯小体提取的RNA的体外翻译；斯坦尼斯小体（PCS）中甲状旁腺素前体的鉴定]
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[Structural similarities between the hypocalcemia hormone of the corpuscles of Stannius of the eel (Anguilla anguilla L.) and the mammalian parathyroid hormone].[鳗鲡（Anguilla anguilla L.）斯坦尼小体低钙血症激素与哺乳动物甲状旁腺激素之间的结构相似性]
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[Comparative effects of an extract of Anguilla Stannius corpuscles and of an active fragment of human parathyroid hormone (1-34 hPTH) on an anuran batracian, Xenopus laevis].[鳗鲡斯坦尼斯小体提取物与人甲状旁腺激素活性片段（1-34 hPTH）对无尾两栖动物非洲爪蟾的比较效应]
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Immunocytochemical localization of parathyroid hormone in bovine parathyroid glands and human parathyroid adenomas.甲状旁腺激素在牛甲状旁腺和人甲状旁腺腺瘤中的免疫细胞化学定位。
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[Intervention of the corpuscles of Stannius in the phosphocalcic equilibrium of the internal environment in a teleost fish, the eel].[斯坦尼斯小体对硬骨鱼（鳗鱼）内环境磷钙平衡的干预]
C R Acad Hebd Seances Acad Sci D. 1967 Jan 30;264(5):736-7.

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