Lavanya Tiruvilvamala Ramesh, Kumar Pavan, Kok Mun Keong, Ong Siew Mei, Radzi Rozanaliza, Selvarajah Gayathri Thevi
Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
University Veterinary Hospital, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Animals (Basel). 2025 Apr 15;15(8):1138. doi: 10.3390/ani15081138.
Ceruminous glands are specialized apocrine sweat glands. Neoplastic transformation of these glands is often seen in the external ear canal. Tumors arising from these glands can present a diagnostic dilemma because of their varied clinical and histological manifestations. This study was conducted as little information is currently available on these neoplasms. The present study undertakes a scoping review of research on canine and feline CGTs according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines for scoping reviews on three databases (NCBI-PubMed, Scopus and ScienceDirect) from 1980 to 2023 (43 years) to determine the extent of the existing literature on its clinicopathological characteristics, overall prognosis, survival rates, and biomarker studies. Seventeen canine and nineteen feline publications that met the inclusion criteria were analyzed. Eleven canine and twelve feline unpublished cases of CGTs managed in Malaysia were also reviewed. Our study concluded surgical excision as part of the treatment for this neoplasia may lengthen animals' survival period and produce a satisfactory quality of life; however, a substantial risk of complications, especially after aggressive surgical excision, exists.
耵聍腺是一种特殊的顶泌汗腺。这些腺体的肿瘤性转化常见于外耳道。由于这些腺体肿瘤的临床和组织学表现多样，其诊断可能会面临困境。目前关于这些肿瘤的信息较少，因此开展了本研究。本研究根据系统评价和Meta分析的首选报告项目（PRISMA）指南，对1980年至2023年（43年）期间在三个数据库（NCBI-PubMed、Scopus和ScienceDirect）上关于犬猫耵聍腺肿瘤（CGTs）的研究进行了范围综述，以确定现有文献中关于其临床病理特征、总体预后、生存率和生物标志物研究的范围。分析了17篇符合纳入标准的犬类文献和19篇猫类文献。还回顾了马来西亚管理的11例犬类和12例猫类未发表的CGTs病例。我们的研究得出结论，手术切除作为这种肿瘤的治疗方法之一，可能会延长动物的生存期并产生令人满意的生活质量；然而，存在并发症的重大风险，尤其是在积极的手术切除后。
