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住院犬猫低镁血症的发病率:一项回顾性研究。

Dysmagnesemia Incidence in Hospitalized Dogs and Cats: A Retrospective Study.

作者信息

Perini Francesca, Di Franco Chiara, Briganti Angela

机构信息

Department of Veterinary Science, University of Pisa, 56124 Pisa, Italy.

出版信息

Animals (Basel). 2025 Apr 18;15(8):1169. doi: 10.3390/ani15081169.

Abstract

Magnesium plays a vital role in the body. This retrospective study aimed to evaluate dysmagnesemia incidence in hospitalized patients. Medical records of 430 dogs and 310 cats were reviewed, including patients with at least one venous blood gas analysis upon admission. Normal ionized magnesium values were considered 0.5-1 mmol/L for both species, according to the machine range. Data collected included patient demographics, hospitalization details, and outcome. In dogs, hypomagnesemia occurred in 35.5%, hypermagnesemia in 1.1%, and normomagnesemia in 62.2%. No survival differences were observed, but males showed a higher hypomagnesemia incidence. Neurological (51%), neoplastic (50%), and endocrine (42%) diseases were most associated with hypomagnesemia. In cats, hypomagnesemia was found in 6.8%, hypermagnesemia in 8%, and normomagnesemia in 85.2%. Hypermagnesemic cats had 2.3 times higher mortality. Endocrine (28.6%), systemic (13.6%), and urinary (12.9%) disorders had a higher incidence of hypermagnesemia. Dysmagnesemia was not linked to hospitalization length or blood pressure changes. In conclusion, dogs showed a high incidence of hypomagnesemia that was not associated with increased mortality. In contrast, although hypermagnesemia had a low incidence in cats, it was associated with increased mortality.

摘要

镁在体内起着至关重要的作用。这项回顾性研究旨在评估住院患者中镁代谢异常的发生率。研究回顾了430只犬和310只猫的病历,包括入院时至少进行过一次静脉血气分析的患者。根据仪器范围,两种动物的正常离子镁值均被认为是0.5 - 1 mmol/L。收集的数据包括患者人口统计学信息、住院详情及预后情况。在犬中,低镁血症发生率为35.5%,高镁血症为1.1%,正常镁血症为62.2%。未观察到生存差异,但雄性犬的低镁血症发生率较高。神经系统疾病(51%)、肿瘤疾病(50%)和内分泌疾病(42%)与低镁血症关联最为密切。在猫中,低镁血症发生率为6.8%,高镁血症为8%,正常镁血症为85.2%。高镁血症的猫死亡率高出2.3倍。内分泌疾病(28.6%)、全身性疾病(13.6%)和泌尿系统疾病(12.9%)高镁血症发生率较高。镁代谢异常与住院时长或血压变化无关。总之,犬的低镁血症发生率较高,但与死亡率增加无关。相比之下,虽然猫的高镁血症发生率较低,但与死亡率增加有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/076e/12024414/f3d2cc489b2c/animals-15-01169-g001.jpg

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